---
product_id: 133086928
title: "Kirkman - Biofilm Defense Disruptor and Buster - W/Lipase and Glucoamylase - Enzymes for Digestion for Men and Women - Protects Immune System - 60 Supplement Capsules"
brand: "kirkman"
price: "VT23642"
currency: VUV
in_stock: true
reviews_count: 8
category: "Kirkman"
url: https://www.desertcart.vu/products/133086928-kirkman-biofilm-defense-disruptor-and-buster-w-lipase-and-glucoamylase
store_origin: VU
region: Vanuatu
---

# Hypoallergenic & gentle on sensitive GI tracts Proprietary enzyme blend dissolves biofilms Supports immune system & microbiome balance Kirkman - Biofilm Defense Disruptor and Buster - W/Lipase and Glucoamylase - Enzymes for Digestion for Men and Women - Protects Immune System - 60 Supplement Capsules

**Brand:** kirkman
**Price:** VT23642
**Availability:** ✅ In Stock

## Summary

> 🛡️ Unlock your body's defense with Kirkman's Biofilm Defense – because health is the ultimate power move.

## Quick Answers

- **What is this?** Kirkman - Biofilm Defense Disruptor and Buster - W/Lipase and Glucoamylase - Enzymes for Digestion for Men and Women - Protects Immune System - 60 Supplement Capsules by kirkman
- **How much does it cost?** VT23642 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.vu](https://www.desertcart.vu/products/133086928-kirkman-biofilm-defense-disruptor-and-buster-w-lipase-and-glucoamylase)

## Best For

- kirkman enthusiasts

## Why This Product

- Trusted kirkman brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Trusted & Proven:** Highly rated with thousands of users experiencing rapid relief and lasting digestive balance.
- • **Gentle Yet Powerful:** Formulated without harsh proteases, perfect for sensitive stomachs and daily use from age 4+.
- • **Clean & Hypoallergenic:** Free from common allergens like dairy, nuts, soy, and gluten—because your wellness deserves purity.
- • **Immune System Guardian:** Supports optimal immune function by disrupting harmful microbial shields that evade your body's protection.
- • **Breakthrough Biofilm Buster:** Exclusive enzyme combo targets and dissolves stubborn biofilms, unlocking your body's natural defenses.

## Overview

Kirkman Biofilm Defense Disruptor is a scientifically formulated enzyme supplement designed to break down biofilms—protective layers that shield harmful microbes—thereby enhancing immune system efficiency and digestive health. Featuring a unique blend including lipase and glucoamylase, it supports microbiome balance while being hypoallergenic and gentle enough for daily use by adults and children over 4 years old. Packaged in a convenient 60-capsule bottle, this gluten-free, vegetarian-friendly formula is a trusted choice for those seeking advanced digestive and immune support.

## Description

Product description Contains a combination of unique enzymes Supports microbiome balance by degrading biofilm compositions.* Dissolves the sugar and fibrin parts of biofilms Made with no significant amount of protease which can irritate the gastrointestinal tract Supports Digestion of Intestinal Biofilm Aids in the digestion of protein, fats, and carbohydrates* We strive to maintain high purity, quality, and efficacy standards. Try all of our products! Children's Multi-Vitamin Zinc 20MG Vitamin C Biofilm Defense Zinc Sulfate Epsom Salt Cream

Review: I'm The Best Reviewer of ALL Time - This is my husband's account but I'm writing to tell you that this is GOLD in a bottle. I was peeing blood. I took the D-Mannose, drank LOTS of water, took probiotics and there was relief and the bloody pee stopped for a while. I only felt slight relief when I downed a half a bottle of powdered D Mannose for my UTI vs. the teaspoon you are supposed to take of that bottle. As soon as I forgot my dosage of D Mannose oh it was a razor blade feeling out of this world each time I peed. I was up all night in pain like probably when a man discovers a gold digger has him for 18 years. I was up, disturbed by this pain and was unable to sleep so I did a google search and found a blog about this Biofilm stuff. Truth is, I fell asleep and woke up in more pain and begged my husband to find this biofilm stuff at 1-2 am and then I passed out in pain and fell back asleep again. I was desperate. I did not want to pay the 40 bucks but I was in so much pain I didn't care. I didn't want to go 53 million in debt. I'm so glad I did, my relief was INSTANT the next time I peed. I think this might be killing other things as well. I started taking Solaray Yeast Cleanse pills because when you get a bladder infection well, I didn't want anymore pain anywhere else (if you know what I mean) so I just started taking them as a precaution. Normally when I take 6 of these pills on my first day I get terrible systemic yeast die off headaches. Not while taking the Biofilm, honey. Nada. I have noticed a slight runny nose but that is it. Overall, I just FEEL better. This is coming from someone who has a drugstore in the closet, of supplements. I've bought and used so many different ones for this and that over the years. Biofilm is a for sure staple in my house after this. I never understood the concept or even heard of it. Nobody is getting sick around here anymore. Ain't nobody got time fo dat! Amazing product and I'm probably the biggest skeptic of all time, kinda the same way Kanye is the greatest rapper of all time in his brain. If you feel sick when you take this it probably is the die off of whatever isn't supposed to be in your body so you can heal. Remember, you always feel worse before you get better. I had a number of supplements I was cramming down my throat for relief and none of them did anything for the two weeks I suffered. Also, lemon water gave great relief as well. I did cherry juice in my juicer, cranberry... no relief. Who knows, maybe it helped but I didn't notice. Neither did the razor blades coming out of my pee hole. The D Mannose was good but I did get the bloody pee back again from my forgetting to take it... as soon as I took this, literally within the next two times I peed; no more blood and no more razor blades coming out. I'm just so thankful it worked for me right away, the way it did. If this is GOLD in a bottle, call me a gold digger because I'm sure my husband won't mind to go ahead and get down again. Thank you!!! I thought I was going to die before I took this. Thank you ten million times over.
Review: Revisited - I have tried this twice now and both times got a violent reaction. I need some relief from constant UTI's that antibiotics can't cure. The reviews were so great so I really wanted it to work. Both times I tried, empty stomach. Two months in between attempts. Second time, within 3 hours I was nauseous, 4 hours I started vomiting. For the next two hours I vomited off and on, ended up with dry heaves, very painful. I know it probably is effective but evidently some of us can't take it. My loss. I revisited this product because of being desperate to get help. The UTI's persisted and I could no longer take the antibiotics. I went on the BioDefense but could not take it on an empty stomach. I had to put a little something in there before taking the pill. It made me able to tolerate it, I'm not sure how it affected the ability of it to work but the outcome was good. I took it in the morning. In the evening, with food, I took Oregano. I finished a whole bottle. The results are fantastic. I have not had a UTI in 7 months, before this I was getting them every couple of months. I also discovered another plus. I have suffered from h.Pylori and not been able to get rid of it even after multiple times with antibiotics. BioDefense helped me but I was just tested positive again. I think it is because the BioDefense peels away layers of the film and the h.Pylori repopulates. I haven't figured how to work this out yet but I think after the 2 weeks on the antibiotics I will go on BioDefense again and then try the Oregano again. I get very sick, nauseous all day long, with the h.Pylori so I am going to keep on until I can get it under control.

## Features

- UNIQUE PROPRIETARY ENZYME BLEND: Kirkman Biofilm Defense contains a combination of unique enzymes exclusively formulated by Kirkman scientists that can dissolve the sugar and fibrin components of biofilms.*
- SUPPORTS MICROBIOME BALANCE: Biofilm is a slimy substance that protects unhealthy microorganisms from the immune system and allows them to thrive, thus hindering the immune system from functioning optimally.
- SAFE FOR DAILY USE: Formulated for adults and children 4 years or older. Take one capsule daily or as directed by a physician.*
- SENSITIVE FORMULATION: Biofilm Defense lacks any significant amount of protease, which can irritate a sensitive GI tract.*
- HYPOALLERGENIC: Does not contain Milk, Eggs, Fish, Shellfish, Tree Nuts, Peanuts, Wheat, Soy, or Sesame.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07SRDFZM2 |
| Age Range Description | Adult |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #40,300 in Health & Household ( See Top 100 in Health & Household ) #161 in Multi-Enzyme Nutritional Supplements |
| Brand | Kirkman |
| Brand Name | Kirkman |
| Container Type | Bottle |
| Customer Reviews | 4.4 out of 5 stars 841 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Item Dimensions | 2.12 x 2.12 x 3.8 inches |
| Item Form | Capsule |
| Item Weight | 0.05 Kilograms |
| Manufacturer | Kirkman |
| Manufacturer Part Number | 0981R-060 |
| Material Features | Gluten Free, Vegetarian |
| Model Number | KKM51892 |
| Number of Items | 1 |
| Primary Supplement Type | Enzyme |
| Product Benefits | Hypoallergenic |
| Special Ingredients | Biofilm Enzyme |
| Total Servings Per Container | 60.0 |
| UPC | 812325024957 812325022236 |
| Unit Count | 60 Count |

## Product Details

- **Brand:** Kirkman
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Capsule
- **Item Weight:** 0.05 Kilograms
- **Item dimensions L x W x H:** 2.12 x 2.12 x 3.8 inches
- **Primary Supplement Type:** Enzyme
- **Product Benefits:** Hypoallergenic
- **Special Ingredients:** Biofilm Enzyme
- **Unit Count:** 60 Count

## Images

![Kirkman - Biofilm Defense Disruptor and Buster - W/Lipase and Glucoamylase - Enzymes for Digestion for Men and Women - Protects Immune System - 60 Supplement Capsules - Image 1](https://m.media-amazon.com/images/I/51X37OMdfzL.jpg)
![Kirkman - Biofilm Defense Disruptor and Buster - W/Lipase and Glucoamylase - Enzymes for Digestion for Men and Women - Protects Immune System - 60 Supplement Capsules - Image 2](https://m.media-amazon.com/images/I/61DmERhL3FL.jpg)
![Kirkman - Biofilm Defense Disruptor and Buster - W/Lipase and Glucoamylase - Enzymes for Digestion for Men and Women - Protects Immune System - 60 Supplement Capsules - Image 3](https://m.media-amazon.com/images/I/61EtEbvCsWL.jpg)
![Kirkman - Biofilm Defense Disruptor and Buster - W/Lipase and Glucoamylase - Enzymes for Digestion for Men and Women - Protects Immune System - 60 Supplement Capsules - Image 4](https://m.media-amazon.com/images/I/61+mLm-nQuL.jpg)
![Kirkman - Biofilm Defense Disruptor and Buster - W/Lipase and Glucoamylase - Enzymes for Digestion for Men and Women - Protects Immune System - 60 Supplement Capsules - Image 5](https://m.media-amazon.com/images/I/81kE-TB13SL.jpg)

## Questions & Answers

**Q: What is the difference between this and Interfase? im battling systemic candida**
A: Here are the components that each has that the other one does not:

InterFase: larger servings, chitosanase, lysozyme, EDTA

Biofilm Defence: nattokinase, alpha-galactosidase, xylanase, amylase, invertase, lipase

By and large, that's it. There are more sugar and fat enzymes in Biofilm Defense, and more fiber and mineral enzymes/agents in InterFase. I guess deciding depends on the type of biofilm, but both seem reasonably well put together.

**Q: How long did you take it for before seeing results? Thanks**
A: When I took it I got very sick the first time which I thought at first was a herxheimer reaction. However I got so ill I had to discontinue nearly immediately intending to restart after other issues were addressed. However I was contacted stating there was a recall on this & when I researched the recall had to do with a chemo drug contamination. While I wish I could give you better information, this experience left me not trusting the company at all. Taking this put me back in my healing possibly by as much as 6 months.

**Q: Can someone upload a picture of the label? I'm looking for some specific ingredients all in one capsule.**
A: http://www.swansonvitamins.com/kirkman-biofilm-defense-60-capsSupplement FactsServing Size: 1 capsuleServings Per Container: 60 	Amount Per Serving	%Daily ValueNEC proprietary enzyme blend	457 mg	*Pectinase	380 endo-PGU	*Glucoamylase	65 AGU	*Serrazimes®(endo/exo protease)20,000 IU	*Nattozimes®(endo/exo protease)1,000 FU	*Beta-glucanase	60 BGU	*Protease AM	10 AP	*Lipase	2,500 FIP	*Protease 6.0	5,000 HUT	*Alpha-galactosidase	100 GalU	*Xylanase	1,000 XU	*Cellulase	500 CU	*Amylase	300 DU	*Invertase	250 SU	**Daily Value Not Established.

**Q: Will this break down biofilms in the bladder and urinary tract?**
A: Remember....oxalates can cause crystals in the body and can be in the bladder area and mimic bladder infections, so watch yourself for oxalate sensitivities, it could very well be that. As well as biofilm, just a thot for you all. :)

## Customer Reviews

### ⭐⭐⭐⭐⭐ I'm The Best Reviewer of ALL Time
*by T***E on February 19, 2016*

This is my husband's account but I'm writing to tell you that this is GOLD in a bottle. I was peeing blood. I took the D-Mannose, drank LOTS of water, took probiotics and there was relief and the bloody pee stopped for a while. I only felt slight relief when I downed a half a bottle of powdered D Mannose for my UTI vs. the teaspoon you are supposed to take of that bottle. As soon as I forgot my dosage of D Mannose oh it was a razor blade feeling out of this world each time I peed. I was up all night in pain like probably when a man discovers a gold digger has him for 18 years. I was up, disturbed by this pain and was unable to sleep so I did a google search and found a blog about this Biofilm stuff. Truth is, I fell asleep and woke up in more pain and begged my husband to find this biofilm stuff at 1-2 am and then I passed out in pain and fell back asleep again. I was desperate. I did not want to pay the 40 bucks but I was in so much pain I didn't care. I didn't want to go 53 million in debt. I'm so glad I did, my relief was INSTANT the next time I peed. I think this might be killing other things as well. I started taking Solaray Yeast Cleanse pills because when you get a bladder infection well, I didn't want anymore pain anywhere else (if you know what I mean) so I just started taking them as a precaution. Normally when I take 6 of these pills on my first day I get terrible systemic yeast die off headaches. Not while taking the Biofilm, honey. Nada. I have noticed a slight runny nose but that is it. Overall, I just FEEL better. This is coming from someone who has a drugstore in the closet, of supplements. I've bought and used so many different ones for this and that over the years. Biofilm is a for sure staple in my house after this. I never understood the concept or even heard of it. Nobody is getting sick around here anymore. Ain't nobody got time fo dat! Amazing product and I'm probably the biggest skeptic of all time, kinda the same way Kanye is the greatest rapper of all time in his brain. If you feel sick when you take this it probably is the die off of whatever isn't supposed to be in your body so you can heal. Remember, you always feel worse before you get better. I had a number of supplements I was cramming down my throat for relief and none of them did anything for the two weeks I suffered. Also, lemon water gave great relief as well. I did cherry juice in my juicer, cranberry... no relief. Who knows, maybe it helped but I didn't notice. Neither did the razor blades coming out of my pee hole. The D Mannose was good but I did get the bloody pee back again from my forgetting to take it... as soon as I took this, literally within the next two times I peed; no more blood and no more razor blades coming out. I'm just so thankful it worked for me right away, the way it did. If this is GOLD in a bottle, call me a gold digger because I'm sure my husband won't mind to go ahead and get down again. Thank you!!! I thought I was going to die before I took this. Thank you ten million times over.

### ⭐⭐⭐⭐⭐ Revisited
*by K***J on June 4, 2022*

I have tried this twice now and both times got a violent reaction. I need some relief from constant UTI's that antibiotics can't cure. The reviews were so great so I really wanted it to work. Both times I tried, empty stomach. Two months in between attempts. Second time, within 3 hours I was nauseous, 4 hours I started vomiting. For the next two hours I vomited off and on, ended up with dry heaves, very painful. I know it probably is effective but evidently some of us can't take it. My loss. I revisited this product because of being desperate to get help. The UTI's persisted and I could no longer take the antibiotics. I went on the BioDefense but could not take it on an empty stomach. I had to put a little something in there before taking the pill. It made me able to tolerate it, I'm not sure how it affected the ability of it to work but the outcome was good. I took it in the morning. In the evening, with food, I took Oregano. I finished a whole bottle. The results are fantastic. I have not had a UTI in 7 months, before this I was getting them every couple of months. I also discovered another plus. I have suffered from h.Pylori and not been able to get rid of it even after multiple times with antibiotics. BioDefense helped me but I was just tested positive again. I think it is because the BioDefense peels away layers of the film and the h.Pylori repopulates. I haven't figured how to work this out yet but I think after the 2 weeks on the antibiotics I will go on BioDefense again and then try the Oregano again. I get very sick, nauseous all day long, with the h.Pylori so I am going to keep on until I can get it under control.

### ⭐⭐⭐⭐⭐ Effective
*by C***L on August 24, 2025*

Never dealt with candida until more recently when I got oral thrush. It lingered and created a horrible biofilm coating on my tongue so I turned to biofilm disruptors so that medications would be effective. I alternate between kirkman and klaire labs for my disruptors as they contain different enzymes. Both work well but I think kirkman works exceptionally well. If youre dealing with biofilms these should absolutely be taken on an empty stomach away from other pills to maximize the benefits. I take four a day all at once. For me, a brief period of nausea will follow (only sometimes) about 45 min after taking these as the enzymes and lack of food contribute to it. I started getting noticeable results within a few days. Yes theyre expensive, but they work.

## Frequently Bought Together

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*Product available on Desertcart Vanuatu*
*Store origin: VU*
*Last updated: 2026-05-11*