---
product_id: 317470185
title: "S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 6.7 fl. oz. (200mL)"
brand: "douxo"
price: "VT9745"
currency: VUV
in_stock: true
reviews_count: 13
category: "Douxo"
url: https://www.desertcart.vu/products/317470185-s3-calm-shampoo-contains-0-75-ophytrium-soothing-for-itchy
store_origin: VU
region: Vanuatu
---

# Visible relief in 7 days Safe for all life stages, dogs & cats 0.75% Ophytrium for skin soothing S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 6.7 fl. oz. (200mL)

**Brand:** douxo
**Price:** VT9745
**Availability:** ✅ In Stock

## Summary

> 🐕✨ Calm the itch, flaunt the shine — because your pet deserves the best!

## Quick Answers

- **What is this?** S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 6.7 fl. oz. (200mL) by douxo
- **How much does it cost?** VT9745 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.vu](https://www.desertcart.vu/products/317470185-s3-calm-shampoo-contains-0-75-ophytrium-soothing-for-itchy)

## Best For

- douxo enthusiasts

## Why This Product

- Trusted douxo brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Hypoallergenic & Safe:** Gentle enough for long-term use on sensitive skin across all life stages.
- • **Fur-Friendly Hydration:** Detangles and moisturizes to leave coats irresistibly soft, shiny, and healthy.
- • **Vet-Approved Allergy Relief:** Trusted #1 non-prescription brand recommended by US veterinarians for allergic dermatitis.
- • **Fast-Acting Soothing Formula:** Interrupts itching cycle with noticeable results in just 7 days, optimal by 21 days.
- • **Complete Skin Ecosystem Repair:** Ophytrium ingredient helps restore and protect skin’s natural barrier.

## Overview

Douxo S3 Calm Shampoo is a veterinarian-recommended, hypoallergenic formula containing 0.75% Ophytrium designed to soothe itchy, irritated, or allergic skin in dogs and cats. It delivers visible relief within 7 days, moisturizes and detangles fur, and supports long-term skin health for pets of all life stages.

## Description

Formulated to help soothe allergic, itchy or irritated skin of dogs or cats. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the 1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs cats with allergic dermatitis.

Review: Wonderful dog shampoo that soothes irritated skin - This shampoo is awesome! It heals hot spots and has made my dogs fur grow back and her fur is soft! Smells great too!
Review: Excellent relief for itchy, sensitive skin - I bought this shampoo for my dog who suffers from allergies, itching, and irritated skin, especially around the ears. After just a few washes, I noticed a big improvement. The redness and itching were reduced, and my dog seemed much more comfortable. The shampoo is very gentle, has a light scent, and lathers well. It doesn’t dry out the skin and leaves the coat soft and clean. I also like that it’s recommended by veterinarians and contains Ophytrium, which really seems to help calm the skin. If your dog has sensitive skin, allergies, or frequent itching, this shampoo is definitely worth it. I will continue using it and highly recommend it.

## Features

- DOUXO S3 CALM Shampoo helps provide your dog or cat with soothing relief from the discomfort of itching and inflamed skin due to allergies
- #1 non-prescription topical brand used and recommended by US veterinarians for dogs and cats with allergic dermatitis (itchy skin due to allergies)
- Detangles fur and leaves the hair and coat soft and shiny, and helps repair skin ecosystem
- Helps interrupt the vicious cycle of itching, with results seen in as little as 7 days, and the best results seen after 21 days
- Safe for long-term use, for best results use with DOUXO S3 CALM Mousse

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B09478KGJZ |
| ASIN  | B09478KGJZ |
| Age Range Description | All Life Stages |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #1,350 in Pet Supplies ( See Top 100 in Pet Supplies ) #14 in Dog Shampoos |
| Brand Name | Douxo |
| Color | Translucent |
| Customer Reviews | 4.6 4.6 out of 5 stars (3,517) |
| Date First Available | May 5, 2021 |
| Date First Available  | May 5, 2021 |
| Directions | Use as recommended by your veterinarian. Wet the fur with cool water from the neck down. Using 1 pump for every 4 lbs, gently massage shampoo onto skin abnormalities to reach the skin. Repeat until entire body is lightly coated with shampoo and leave on for 10 minutes. Rinse thoroughly with cool water. Shampoo amount can be doubled for dogs or cats with long and/or thick fur. |
| Included Components | Shampoo |
| Item Package Dimensions L x W x H | 6.02 x 2.64 x 1.97 inches |
| Item Weight | 8.8 ounces |
| Item model number | D98110P |
| Item model number  | D98110P |
| Liquid Volume | 6.7 Fluid Ounces |
| Manufacturer | Douxo S3 |
| Manufacturer  | Douxo S3 |
| Material | Liquid |
| Model Name | DOUXO® S3 CALM Shampoo 6.7 oz (200 mL) |
| Number of Items | 1 |
| Package Dimensions  | 6.02 x 2.64 x 1.97 inches; 8.78 ounces |
| Pet Type | Cat, Dog |
| Size | 6.7 oz |
| Special Ingredients | Ophytrium |
| Specific Uses for Product | allergy-relief |
| Target Audience Keyword | Cats, Dogs, dogs |
| Target Species | dog, cat |
| UPC | 850002593389 |

## Product Details

- **Brand:** Douxo
- **Material Type Free:** Hypoallergenic
- **Product Benefits:** Anti-Itch
- **Recommended Uses For Product:** Itchy
- **Scent:** Fresh, Sweet

## Images

![S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 6.7 fl. oz. (200mL) - Image 1](https://m.media-amazon.com/images/I/61fIkdZDoiL.jpg)

## Available Options

This product comes in different **Size** options.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Wonderful dog shampoo that soothes irritated skin
*by N***E on February 25, 2026*

This shampoo is awesome! It heals hot spots and has made my dogs fur grow back and her fur is soft! Smells great too!

### ⭐⭐⭐⭐⭐ Excellent relief for itchy, sensitive skin
*by M***A on December 20, 2025*

I bought this shampoo for my dog who suffers from allergies, itching, and irritated skin, especially around the ears. After just a few washes, I noticed a big improvement. The redness and itching were reduced, and my dog seemed much more comfortable. The shampoo is very gentle, has a light scent, and lathers well. It doesn’t dry out the skin and leaves the coat soft and clean. I also like that it’s recommended by veterinarians and contains Ophytrium, which really seems to help calm the skin. If your dog has sensitive skin, allergies, or frequent itching, this shampoo is definitely worth it. I will continue using it and highly recommend it.

### ⭐⭐⭐⭐⭐ A Lifesaver for My Dog’s Skin — Worth Every Penny
*by A***N on June 17, 2025*

I’ve tried a lot of products to manage my dog’s skin issues, but Douxo S3 Calm is the only shampoo that’s consistently helped. My golden retriever, Luna, has a dust mite allergy and a history of sensitive skin and occasional staph infections, especially when staying in dusty or older environments. This shampoo has become part of our routine, and it’s made a real difference. It’s gentle, fragrance-free, and doesn’t dry her out — even with more frequent use. Her skin looks calmer, less red, and she scratches way less after a bath. I’ve noticed fewer flare-ups since switching to this and sticking to a consistent bathing schedule. If your dog has allergy-prone or reactive skin like mine, this is the one to try. It’s pricey, but it actually works — and that’s what matters.

## Frequently Bought Together

- Douxo S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 6.7 fl. oz. (200mL)
- Douxo S3 Calm Mousse, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 5.1 fl. oz. (150mL)
- Douxo S3 Pyo Pads, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 30 Pads

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*Product available on Desertcart Vanuatu*
*Store origin: VU*
*Last updated: 2026-05-18*