--- product_id: 317470190 title: "Douxo S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 16.9 fl. oz. (500mL)" brand: "douxo" price: "VT17053" currency: VUV in_stock: true reviews_count: 13 category: "Douxo" url: https://www.desertcart.vu/products/317470190-douxo-s3-calm-shampoo-contains-0-75-ophytrium-soothing-itchy store_origin: VU region: Vanuatu --- # Visible relief in 7 days 0.75% Ophytrium for skin calm Vet-recommended for dogs & cats Douxo S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 16.9 fl. oz. (500mL) **Brand:** douxo **Price:** VT17053 **Availability:** ✅ In Stock ## Summary > 🐾 Calm skin, happy pets — because they deserve the best! ## Quick Answers - **What is this?** Douxo S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 16.9 fl. oz. (500mL) by douxo - **How much does it cost?** VT17053 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.vu](https://www.desertcart.vu/products/317470190-douxo-s3-calm-shampoo-contains-0-75-ophytrium-soothing-itchy) ## Best For - douxo enthusiasts ## Why This Product - Trusted douxo brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Hypoallergenic & Safe:** Paraben and sulfate-free formula designed for long-term use on sensitive skin. - • **Soft & Shiny Coat Boost:** Detangles fur while moisturizing, leaving your pet’s coat irresistibly soft and glossy. - • **Vet-Approved Allergy Relief:** Trusted #1 non-prescription brand recommended by US veterinarians for allergic dermatitis. - • **Fast-Acting Soothing Formula:** Interrupts itching cycle with noticeable comfort in just 7 days, best results by 21 days. - • **Complete Skin Ecosystem Repair:** Ophytrium ingredient helps restore and protect your pet’s skin barrier for lasting calm. ## Overview Douxo S3 Calm Shampoo features 0.75% Ophytrium, a vet-recommended hypoallergenic formula that soothes itchy, irritated skin in dogs and cats. Clinically proven to reduce itching within 7 days, it also detangles and moisturizes fur, leaving coats soft and shiny. Free from parabens and sulfates, it’s safe for long-term use and supports skin barrier repair for lasting relief. ## Description Formulated to help soothe allergic, itchy or irritated skin of dogs or cats. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the 1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with allergic dermatitis. Review: Wonderful dog shampoo that soothes irritated skin - This shampoo is awesome! It heals hot spots and has made my dogs fur grow back and her fur is soft! Smells great too! Review: Excellent relief for itchy, sensitive skin - I bought this shampoo for my dog who suffers from allergies, itching, and irritated skin, especially around the ears. After just a few washes, I noticed a big improvement. The redness and itching were reduced, and my dog seemed much more comfortable. The shampoo is very gentle, has a light scent, and lathers well. It doesn’t dry out the skin and leaves the coat soft and clean. I also like that it’s recommended by veterinarians and contains Ophytrium, which really seems to help calm the skin. If your dog has sensitive skin, allergies, or frequent itching, this shampoo is definitely worth it. I will continue using it and highly recommend it. ## Features - DOUXO S3 CALM Shampoo helps provide your dog or cat with soothing relief from the discomfort of itching and inflamed skin due to allergies - #1 non-prescription topical brand used and recommended by US veterinarians for dogs and cats with allergic dermatitis (itchy skin due to allergies) - Detangles fur and leaves the hair and coat soft and shiny, and helps repair skin ecosystem - Helps interrupt the vicious cycle of itching, with results seen in as little as 7 days, and the best results seen after 21 days - Safe for long-term use, for best results use with DOUXO S3 CALM Mousse ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B09478KSWG | | ASIN | B09478KSWG | | Allergen Information | Hypoallergenic | | Best Sellers Rank | #1,323 in Pet Supplies ( See Top 100 in Pet Supplies ) #13 in Dog Shampoos | | Brand Name | Douxo | | Customer Reviews | 4.6 4.6 out of 5 stars (3,628) | | Date First Available | May 5, 2021 | | Included Components | Shampoo | | Item Form | Mousse | | Item Type Name | Shampoos & Conditioners | | Item Weight | 16.9 Ounces | | Item model number | D98120F | | Liquid Volume | 16.9 Fluid Ounces | | Manufacturer | Douxo S3 | | Manufacturer | Douxo S3 | | Material Type Free | Paraben Free, Sulfate Free | | Package Dimensions | 7.32 x 3.46 x 1.93 inches; 1.06 Pounds | | Product Benefits | Anti-Itch | | Recommended Uses For Product | Irritated Skin | | Scent Name | Fresh, Sweet | | Special Ingredients | OPHYTRIUM | | Target Species | dog, cat | | UPC | 850002593396 | | Unit Count | 1 Count | ## Product Details - **Brand:** Douxo - **Material Type Free:** Paraben Free, Sulfate Free - **Product Benefits:** Anti-Itch - **Recommended Uses For Product:** Irritated Skin - **Scent:** Fresh, Sweet ## Images ![Douxo S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 16.9 fl. oz. (500mL) - Image 1](https://m.media-amazon.com/images/I/61UXvYF3RzL.jpg) ## Available Options This product comes in different **Size** options. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Wonderful dog shampoo that soothes irritated skin *by N***E on February 25, 2026* This shampoo is awesome! It heals hot spots and has made my dogs fur grow back and her fur is soft! Smells great too! ### ⭐⭐⭐⭐⭐ Excellent relief for itchy, sensitive skin *by M***A on December 20, 2025* I bought this shampoo for my dog who suffers from allergies, itching, and irritated skin, especially around the ears. After just a few washes, I noticed a big improvement. The redness and itching were reduced, and my dog seemed much more comfortable. The shampoo is very gentle, has a light scent, and lathers well. It doesn’t dry out the skin and leaves the coat soft and clean. I also like that it’s recommended by veterinarians and contains Ophytrium, which really seems to help calm the skin. If your dog has sensitive skin, allergies, or frequent itching, this shampoo is definitely worth it. I will continue using it and highly recommend it. ### ⭐⭐⭐⭐⭐ Amazing! *by A***G on March 15, 2026* This is the only shampoo that has relieved my dog’s itching and healed her skin. It also has improved her fur and allowed it to grown back in the spots it had fallen out. I shampoo her with this every couple weeks and will continue to do so! ## Frequently Bought Together - Douxo S3 Calm Shampoo 16.9 oz (500 mL) - For Dogs and Cats with Itchy Skin, Translucent - Douxo S3 Calm Mousse 5.1 oz (150 mL) - For Dogs and Cats with Allergic, Itchy Skin - Douxo S3 PYO Shampoo 16.9 oz (500 mL) --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.vu/products/317470190-douxo-s3-calm-shampoo-contains-0-75-ophytrium-soothing-itchy](https://www.desertcart.vu/products/317470190-douxo-s3-calm-shampoo-contains-0-75-ophytrium-soothing-itchy) --- *Product available on Desertcart Vanuatu* *Store origin: VU* *Last updated: 2026-05-04*