---
product_id: 332860117
title: "PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being"
brand: "pranapets"
price: "VT14277"
currency: VUV
in_stock: true
reviews_count: 8
category: "Prana Pets"
url: https://www.desertcart.vu/products/332860117-pranapets-lignans-and-melatonin-with-biotin-blend-naturally-aids-in
store_origin: VU
region: Vanuatu
---

# 10 mg SDG Lignans from Flax Seed Extract Formulated specifically for large dog breeds 1 mg Melatonin per tablet PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being

**Brand:** pranapets
**Price:** VT14277
**Availability:** ✅ In Stock

## Summary

> 🐾 Elevate your dog’s health game with nature’s adrenal ally!

## Quick Answers

- **What is this?** PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being by pranapets
- **How much does it cost?** VT14277 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.vu](https://www.desertcart.vu/products/332860117-pranapets-lignans-and-melatonin-with-biotin-blend-naturally-aids-in)

## Best For

- pranapets enthusiasts

## Why This Product

- Trusted pranapets brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Long-Term Wellness:** Supports your dog’s vitality and calmness over time
- • **Vet-Approved Formula:** Trusted by professionals with proven blood lab improvements
- • **Natural Adrenal Balance:** Harnesses plant-based lignans for holistic hormone support
- • **Peanut Butter Flavor Boost:** Delicious taste ensures easy daily dosing without fuss
- • **Targeted Cushing’s Relief:** Clinically backed blend to ease hair loss & cortisol spikes

## Overview

PranaPets Lignans & Melatonin Blend is a vet-endorsed supplement designed to naturally alleviate symptoms of Cushing’s Disease in large dogs. Each tablet delivers 1 mg of melatonin and 10 mg of SDG lignans from flax seed extract, promoting healthy adrenal function, cortisol balance, and overall well-being. Its peanut butter flavor ensures easy administration, making it a trusted choice for long-term adrenal support and improved quality of life.

## Description

desertcart.com : PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being : Pet Supplies

Review: Really helped calm my doggy and let her get rest - My little doggie was diagnosed with Cushing disease. In the evenings especially she was miserable. This medicine helped to calm her and let her rest. I still ended up putting her on vet prescribed medicine, but this really helped us get thru that period before testing to get her on meds. I was hoping it and the other homeopathic meds we tried would work, but after a couple of months it didn’t seem to be enough. I will still use and recommend this product as it really did help settle her down. On nights when she needs a little extra help, I still give her some.
Review: I 100% believe this supplement saved my Boston Terrier - We were flirting with a Cushing diagnosis about six months ago, but were unable to confirm with certainty. A friend asked Dr. Google and sent me a link to this product. If you’re familiar with adrenal Cushings and traditional diagnosis and treatment, it’s time consuming and EXPENSIVE. I think had we gone with Vetoryl, she’d still be going in for semi-regular labs (all day, fasting, couple hundred bucks a pop) to get dosage right. I didn’t feel I had much to lose, started her on one pill daily, and noticed a difference in less than a week. Proof came with her checkup this fall, in less than 6 months her ALP went from 1622 in April to 470! Our vet was amazed. One note: at first, she would not eat it solo and it’s too big to hide in food. I bought a cheap pill crusher and used that for a while. Now, I just toss a pill into her bowl of kibble and she eats it fine.

## Features

- 𝐂𝐔𝐒𝐇𝐈𝐍𝐆’𝐒 𝐒𝐔𝐏𝐏𝐎𝐑𝐓 – Melatonin and lignans together help manage the symptoms of Cushing’s, such as excessive thirst, panting and urination. Get even better results when used with Prana Pets Adrenal Balance.
- HEALTHY CORTISOL LEVELS - Adjusted for more effective support in lowering cortisol levels, especially helpful for dogs with Cushing’s.
- NEW FORMULA - Improved Lignans and Melatonin Blend formula offers more precise dosing with new added benefits. Now with adjusted amounts of SDG lignans and melatonin for more accurate dosing.
- ADDED BIOTIN - Now includes biotin for healthier skin, coat and nails. Promotes a shiny coat, healthy skin and strong nails while helping to reduce hot spots and hair loss.
- LESS JUNK - No more artificial flavors, sorbitol and sucrose so you can worry less about what you are giving your beloved pooch. Non-GMO, Gluten & Soy Free.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0DFJCL5BG |
| ASIN  | B0DFJCL5BG |
| Active Ingredients | Active Ingredients per 2 tablets: SDG Lignans (from Flaxseed Extract)…80 mg, Melatonin…6 mg, Biotin…3 mg |
| Allergen Information | Non-GMO |
| Best Sellers Rank | #6,880 in Pet Supplies ( See Top 100 in Pet Supplies ) #33 in Dog Herbal Supplements |
| Brand Name | PranaPets |
| Customer Reviews | 4.5 4.5 out of 5 stars (64) |
| Date First Available  | August 22, 2024 |
| Flavor | Beef |
| Included Components | Tablets |
| Item Type Name | Better Sleep, Calming |
| Item Weight | 0.09 Kilograms |
| Item model number  | PPMELLIG2-BIO |
| Manufacturer | PranaPets |
| Manufacturer  | PranaPets |
| Package Dimensions  | 3.78 x 1.93 x 1.89 inches; 3.21 ounces |
| Product Benefits | Anti-Hairfall, Cushing's relief for dogs, Immune Support, Skin Care |
| UPC | 850067825012 |
| Unit Count | 1.0 Count |
| Warranty Description | 366 |

## Product Details

- **Brand:** PranaPets
- **Flavor:** Beef
- **Item Weight:** 0.09 Kilograms
- **Product Benefits:** Anti-Hairfall, Cushing's relief for dogs, Immune Support, Skin Care

## Images

![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 1](https://m.media-amazon.com/images/I/61r5wEqvgLL.jpg)
![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 2](https://m.media-amazon.com/images/I/61beYML0zDL.jpg)
![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 3](https://m.media-amazon.com/images/I/611zPlTqhYL.jpg)
![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 4](https://m.media-amazon.com/images/I/61T+VAV3mSL.jpg)
![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 5](https://m.media-amazon.com/images/I/61nM8KYVoIL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: What is new and improved about this formula?**
A: Our improved Lignans and Melatonin Blend formula offers more precise dosing with new added benefits. Now with adjusted amounts of SDG lignans and melatonin for more accurate dosing, plus biotin for a healthier skin, coat, and nails.

**Q: Can I use Lignans and Melatonin with other Prana Pets supplements?**
A: Absolutely! We recommend combining our supplements for a full daily health regimen. Our proprietary blends were formulated to work together synergistically to keep your pet looking and feeling their best.

**Q: What other supplements should I give my Cushing's dog?**
A: We recommended Adrenal Balance, Lignans and Melatonin, Immunity Blend and Liver Supplement for full Cushing's support.

**Q: Should this product only be used for Cushing's dogs?**
A: No! Lignans and Melatonin is great for any nervous or high-strung dog who suffers from things like separation anxiety or other phobias. It's great to calm nerves for trips to the vet or during loud 4th of July fireworks, too.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Really helped calm my doggy and let her get rest
*by B***H on February 28, 2026*

My little doggie was diagnosed with Cushing disease. In the evenings especially she was miserable. This medicine helped to calm her and let her rest. I still ended up putting her on vet prescribed medicine, but this really helped us get thru that period before testing to get her on meds. I was hoping it and the other homeopathic meds we tried would work, but after a couple of months it didn’t seem to be enough. I will still use and recommend this product as it really did help settle her down. On nights when she needs a little extra help, I still give her some.

### ⭐⭐⭐⭐⭐ I 100% believe this supplement saved my Boston Terrier
*by D***T on November 1, 2025*

We were flirting with a Cushing diagnosis about six months ago, but were unable to confirm with certainty. A friend asked Dr. Google and sent me a link to this product. If you’re familiar with adrenal Cushings and traditional diagnosis and treatment, it’s time consuming and EXPENSIVE. I think had we gone with Vetoryl, she’d still be going in for semi-regular labs (all day, fasting, couple hundred bucks a pop) to get dosage right. I didn’t feel I had much to lose, started her on one pill daily, and noticed a difference in less than a week. Proof came with her checkup this fall, in less than 6 months her ALP went from 1622 in April to 470! Our vet was amazed. One note: at first, she would not eat it solo and it’s too big to hide in food. I bought a cheap pill crusher and used that for a while. Now, I just toss a pill into her bowl of kibble and she eats it fine.

### ⭐⭐⭐⭐⭐ Effective
*by P***E on April 14, 2026*

Seems to work great

## Frequently Bought Together

- PranaPets Lignans & Melatonin Blend Naturally Aids in Relieving Symptoms of Cushing's Disease in Dogs | Helps Promote Healthy Adrenal Balance & Overall Well-Being | 1 MG Melatonin, 10 MG Lignans
- PranaPets Adrenal Balance for Dogs with Cushing’s | Naturally Relieves Symptoms of Cushing's in Dogs | Herbal Formula for Dogs with Cushing’s
- Аdrеnаl Balance for Dogs and Cats - Cushings Treatment for Pets, Аdrеnаl Support w/Ashwagandha, Licorice Root, Rhodiola Rosea – Best Cushings Treatment for Dogs - 2oz Harmony Herbal Drops

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*Product available on Desertcart Vanuatu*
*Store origin: VU*
*Last updated: 2026-05-03*