--- product_id: 3403144 title: "Plus for Dogs Large Dog (45 to 88 pounds) Flea and Tick Treatment, 6 Doses" brand: "frontline" price: "VT23311" currency: VUV in_stock: true reviews_count: 9 category: "Frontline" url: https://www.desertcart.vu/products/3403144-plus-for-dogs-large-dog-45-to-88-pounds-flea store_origin: VU region: Vanuatu --- # Waterproof after 24 hrs 1-month lasting protection Fast-acting in 24 hrs Plus for Dogs Large Dog (45 to 88 pounds) Flea and Tick Treatment, 6 Doses **Brand:** frontline **Price:** VT23311 **Availability:** ✅ In Stock ## Summary > 🐾 Protect your best friend like a pro — no fleas, no ticks, no worries! ## Quick Answers - **What is this?** Plus for Dogs Large Dog (45 to 88 pounds) Flea and Tick Treatment, 6 Doses by frontline - **How much does it cost?** VT23311 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.vu](https://www.desertcart.vu/products/3403144-plus-for-dogs-large-dog-45-to-88-pounds-flea) ## Best For - frontline enthusiasts ## Why This Product - Trusted frontline brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Waterproof Confidence:** Keeps working even if your dog gets wet after 24 hours - • **Break the Flea Life Cycle:** Kills adult fleas, eggs, larvae & ticks for total pest control - • **Trusted for Over 20 Years:** Proven reliability with millions of happy pet owners worldwide - • **Effortless Monthly Defense:** Easy single-spot application for a full 30 days of protection - • **Peace of Mind Subscription:** Never run out with convenient auto-delivery for year-round defense ## Overview Frontline Plus for Large Dogs delivers fast, waterproof, and long-lasting flea and tick protection with a single monthly topical dose. Trusted for over 20 years, it kills adult fleas, eggs, larvae, ticks, and lice, breaking the pest life cycle and keeping your dog comfortable and pest-free even after swimming or bathing. ## Description Product Description Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention. Brand Story By Frontline Plus Review: Finally found something that actually works! - After trying at least four different flea treatments that barely made a dent, I'm so relieved to have found these drops. They actually work - and work fast. We have two dogs who love being outside, and fleas have been an ongoing battle, especially during the warmer months. Within 24 hours of applying these drops, I noticed a huge difference. The scratching stopped, and when I checked them over, the fleas were gone. It's been several weeks now and still no sign of them coming back. Application is easy - just part the fur at the back of the neck and squeeze the tube. My dogs don't seem bothered by it at all, and it dries quickly so they can go about their day. The protection lasts the full month as advertised, which is more than I can say for some of the other brands we've tried. I've set up a subscription so I never run out because I'm not going back to the constant scratching and discomfort my pups were dealing with before. If you've been struggling to find an effective flea treatment, I highly recommend giving these a try. They've been a game-changer for us. Worth every penny for the peace of mind and happy, comfortable dogs! Review: ⭐️⭐️⭐️⭐️⭐️ - Reliable flea & tick protection I’ve been using this flea and tick treatment for my dog, and it’s worked really well. It’s easy to apply, and I like that it provides long-lasting protection without needing to constantly reapply. I’ve noticed a big difference—no fleas, no ticks, and my dog hasn’t had any issues or reactions to it. It gives me peace of mind, especially during the warmer months when pests are the worst. Definitely a dependable option if you’re looking to keep your dog protected! ## Features - Provides fast-acting, long-lasting flea and tick protection for pets 8 weeks or older - Kills adult fleas, ticks, chewing lice, mites, and flea eggs and larvae - Waterproof 24 hours after application - Easy to apply for once a month for lasting protection - For best results, apply every month ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0002J1FOO | | ASIN | B0002J1FOO | | Active Ingredients | fipronil and (S)-methoprene | | Age Range Description | All Life Stages | | Allergen Information | Abalone Free | | Best Sellers Rank | #84 in Pet Supplies ( See Top 100 in Pet Supplies ) #2 in Dog Flea Drops | | Brand Name | Frontline | | Customer Reviews | 4.4 4.4 out of 5 stars (49,788) | | Date First Available | October 2, 2001 | | Department | Pet Supplies | | Dog Breed Size | Large | | Included Components | Package includes 6 applicators | | Is Discontinued By Manufacturer | No | | Item Form | Liquid | | Item Type Name | Topical Purple box | | Item Weight | 0.2 Ounces | | Item model number | 72219 | | Manufacturer | Boehringer Ingelheim Animal Health | | Manufacturer | Boehringer Ingelheim Animal Health | | Manufacturer Part Number | 605388958174 | | Manufacturer recommended age | 1 month and up | | Model Number | 72219 | | Product Dimensions | 5.75 x 1 x 4.5 inches; 0.2 ounces | | Scent Name | Unscented | | Target Species | Dog | | UPC | 605388958174 701002620738 634252111407 794712170624 010701820043 643396060175 891962001187 897786529487 764527051814 788995790211 634252076362 350604288206 717077006667 609456799225 712542174193 609456799263 813471010955 288210000007 712542174094 | | Unit Count | 6 Count | | Volume | 1 Milliliters | | Warranty Description | only for dogs | ## Product Details - **Active Ingredients:** fipronil and (S)-methoprene - **Age Range (Description):** All Life Stages - **Allergen Information:** Abalone Free - **Brand:** Frontline - **Dog Breed Size:** Large - **Item Form:** Liquid - **Item Volume:** 1 Milliliters - **Item Weight:** 0.2 Ounces - **Scent:** Unscented ## Images ![Plus for Dogs Large Dog (45 to 88 pounds) Flea and Tick Treatment, 6 Doses - Image 1](https://m.media-amazon.com/images/I/711CF6-d1KL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: effectiveness** A: Ive never had a flea problem with frontline, but for ticks they would attach to the dog before it died. So i switched to the seresto 8 month collar. The 1st one i used worked great no issues. The 2nd one (8months later) had the same date as the first one. I dont know if that was an issue but the collar stopped working after 5 months and we ended up with fleas. First time that we ever had fleas. So i am going back to frontline. My concerns are the date on package and where its coming from. **Q: can i use this on my cat?** A: Hi, Thank you for your question! This specific product and formula is only intended for large dogs and puppies 45 - 88 lbs and should not be applied to cats. We have Frontline Plus for Cats 6 dose that is specifically formulated to treat your Cats & Kittens 1.5 lbs and above for 6 full months of protection. If you have any additional questions, please call our experts at 1-800-660-1842. **Q: how soon after use, can I bathe dog with shampoo** A: "FRONTLINE Plus remains effective for 30 days, even if your pet swims or is bathed. After application, keep your pet from getting wet for 24 hours. If FRONTLINE Plus is to be applied after a bath, make sure your pet is completely dry before application. "I would also wait a few extra days if there are fleas in your carpet or if the dog is around bark dust because you can't reapply it if you wash it off prematurely. I try to wait until I have vacuumed the house a few times. Also, it takes a starving flea a couple of days to die. I totally understand not wanting to touch that wet spot on puppy's neck. This is a small sacrifice. Good luck! I am a firm believer in frontline. **Q: is it a pill?** A: No, this is a topical solution not a pill. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Finally found something that actually works! *by R***Z on February 9, 2026* After trying at least four different flea treatments that barely made a dent, I'm so relieved to have found these drops. They actually work - and work fast. We have two dogs who love being outside, and fleas have been an ongoing battle, especially during the warmer months. Within 24 hours of applying these drops, I noticed a huge difference. The scratching stopped, and when I checked them over, the fleas were gone. It's been several weeks now and still no sign of them coming back. Application is easy - just part the fur at the back of the neck and squeeze the tube. My dogs don't seem bothered by it at all, and it dries quickly so they can go about their day. The protection lasts the full month as advertised, which is more than I can say for some of the other brands we've tried. I've set up a subscription so I never run out because I'm not going back to the constant scratching and discomfort my pups were dealing with before. If you've been struggling to find an effective flea treatment, I highly recommend giving these a try. They've been a game-changer for us. Worth every penny for the peace of mind and happy, comfortable dogs! ### ⭐⭐⭐⭐⭐ ⭐️⭐️⭐️⭐️⭐️ *by K***A on March 23, 2026* Reliable flea & tick protection I’ve been using this flea and tick treatment for my dog, and it’s worked really well. It’s easy to apply, and I like that it provides long-lasting protection without needing to constantly reapply. I’ve noticed a big difference—no fleas, no ticks, and my dog hasn’t had any issues or reactions to it. It gives me peace of mind, especially during the warmer months when pests are the worst. Definitely a dependable option if you’re looking to keep your dog protected! ### ⭐⭐⭐⭐⭐ This is hands-down the best flea and tick preventative made *by L***S on January 12, 2016* This is hands-down the best flea and tick preventative made. I've tried others, such as Revolution, and would end up having to pick literally 20-50 attached ticks off my dog every time we went hiking and that was pretty much every day. Then they'd get in the house and be crawling on bedsheets and even across the keyboard of the computer - total nightmare. Since using Frontline, I rarely find any. Once in a while I'll find one or maybe two, but they're crawling on top of her fur and never attached. Since using Frontline, I haven't once found an attached tick on my dog nor my mom and dad's dog who is also treated with Frontline. They have had the same experience with their dog - the other brands just plain don't work - at least not for ticks, which is the main issues that we deal with, being that we live in the mountains and hike with the dogs almost ever day. Frontline works. Period. My only caveat is that you can't use this for people, which tells me that it's pretty toxic and that's why I'm giving it 4 stars instead of 5. It's pretty nasty stuff, you're supposed to avoid getting in on your skin and wash your hands immediately afterwards. If it's that toxic to humans, how safe can it be for our dogs? I really don't like the idea of putting something that's too toxic for humans on my dog and neither do my mom and dad. If we lived in the city and/or ticks weren't such an issue, we wouldn't use it. However, because of where we live and our lifestyle, the risks of tick-borne diseases outweigh the risks of the toxicity of the medicine. It's worth it for us. Decide for yourself if it's worth it for you. ## Frequently Bought Together - Frontline Plus for Dogs Large Dog (45 to 88 pounds) Flea and Tick Treatment, 6 Doses - Frontline Plus for Dogs Medium Dog (23-44 pounds) Flea and Tick Treatment, 6 Doses - Frontline Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 6 Treatments --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.vu/products/3403144-plus-for-dogs-large-dog-45-to-88-pounds-flea](https://www.desertcart.vu/products/3403144-plus-for-dogs-large-dog-45-to-88-pounds-flea) --- *Product available on Desertcart Vanuatu* *Store origin: VU* *Last updated: 2026-05-02*