Nature Made SAM-e Complete 400 mg, Dietary Supplement for Mood Support, 36 Tablets, 36 Day Supply

May be a placebo but it’s working for me. Takes irritably down a notch and makes my energy level higher. I take them usually first thing in the morning with a glass of water.

Good product

Seems to work well

Great buy at works but I am taking two 400 mg tabs daily.Is up to you what works for you

This stuff works wonders!I went through a pretty rough patch in my life. I lost 2 dogs, 1 cat, and my best friend/roommate to cancer all within 2 years.My doctor placed me on Welbutrin but that stuff made me completely insane! 1 day I was angry, 1 day I was completely miserable, 1 day I was unbearably tired. I also had a horrible headache when I was taking it. I felt like was a mindless zombie on Welbutrin. I decided to stop taking the Welbutrin before it settled into my system.I figured I would try and go the more natural route after reading all the side effects of the other anti-depressant medications they have available. I first tried Kira St Johns Wort Tablets - 45 Tablets. These seemed to help, but it was very mild and not consistent in keeping my mood up.Then...there was Nature Made Sam-E. I tried some of the store brand Sam-E's to try and keep costs down, however, none of the other brands even came close to working as good as Nature's Made. And if you shop around you can usually find a buy one get one free at Walgreens, Giant, CVS, or even Amazon!This stuff helped me through the roughest time of my life. I've been using Sam-e well over 2 years now and if I even missed one dose I would immediately notice a huge change in my mood. I have been taking 1 400mg pill a day since I started. Once in a while I would take took 2 or 3 in a day.I just started taking 1 pill every other day to give my body a break because I do not like to be dependent on any type of medication. But for those super hard times, this stuff really helped to get me through.I highly recommend trying Sam-E. Especially before trying any prescription anti-depressants. It is a natural approach to overcoming depression, has low to no side effects at all (I never experienced any), and even if it does not help with improving your mental health, at least it is supporting your joints. ;)Hope this helps!

I have taken Sam-r for more than 15 years. It has helped me to remain "mellow" for the morning rush and later for the lift I needed after the death of my husband it helped me have the energy I needed to go back to classes and fill my time.

Item as described.

My review on this needs a little backstory: I've been taking St. Johns Wort for several years for moderate depression and anxiety. It has changed my life; however, I began to worry about its counteractive effect on birth control. I don't want to use standard pharmaceuticals unless I absolutely have to, so I decided to try Sam-E.Effects of Sam-E on mood: Definite mood boost. Never sank into the very low spots that plagued me before.On energy: Insane energy levels. Useful, but a little scary. For several hours after I took it I was buzzing.On sleep: Gave me moderate insomnia. Again, I didn't feel tired, but not being able to sleep at night was frustrating.On urine?!: Bright highlighter yellow. Florescent pee. That was weird.On stomach: This is where it really got me. I took it after waking up, so empty stomach, and ate 40 minutes to an hour later. For the first week it gave me INTENSE stomach pain for about four hours after taking it. After that first week, the intense pain subsided to a dull ache, but - sorry for the graphics here - it gave me diarrhea every. single. day. Not so good. But since it worked so well at lifting my fatigue, I kept trying it, until week 5...On brain: When the dizziness set in. My brain started swirling around so vigorously I couldn't walk or drive. I actually kept taking it for a week after the dizziness started, because the mental clarity it had given me before was so useful. I didn't want the Sam-E to be the cause. But at week 6 I double checked the list of side effects for Sam-E and yes indeed, dizziness is on it. I switched back to St. Johns and in the weeks since the dizziness has slowly faded away.So, that was a long review, but I wanted to really share my experience. The upsides of Sam-E are very powerful, and since everyone's body reacts a bit differently, it's almost certainly worth a shot if you have anxiety, depression, and fatigue. If Sam-E doesn't work for you, I can recommend from my experience St. Johns Wort. It doesn't give the energy boost but it is a great mood balancer and has never messed with my stomach. I've also heard that 5-HTP can work well for some people, so you might give that a try too.I hope you find something that works for you! Just don't give up and assume that depressed is the only way you can be. As strange as it seems, taking a little plant pill or an enzyme really can be the thing that sets your brain right and gets you on a brighter path. It won't solve all your problems but it can help keep your mind from sabotaging you at every step. :) Good luck.