---
product_id: 661970350
title: "Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct"
brand: "tylenol"
price: "VT5578"
currency: VUV
in_stock: true
reviews_count: 8
category: "Tylenol"
url: https://www.desertcart.vu/products/661970350-extra-strength-severe-cough-sore-throat-day-and-night-caplets
store_origin: VU
region: Vanuatu
---

# 500mg acetaminophen max strength 24 caplets combo pack 16 day + 8 night caplets Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct

**Brand:** tylenol
**Price:** VT5578
**Availability:** ✅ In Stock

## Summary

> 💥 Power through cold & flu season with Tylenol’s day & night multi-symptom relief!

## Quick Answers

- **What is this?** Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct by tylenol
- **How much does it cost?** VT5578 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.vu](https://www.desertcart.vu/products/661970350-extra-strength-severe-cough-sore-throat-day-and-night-caplets)

## Best For

- tylenol enthusiasts

## Why This Product

- Trusted tylenol brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Compact & Convenient:** 24-count combo pack fits perfectly in your medicine cabinet or travel bag — never miss a dose when you need it most.
- • **All-Day & Night Relief:** Tailored formula with 16 daytime and 8 nighttime caplets to keep you powered through every hour.
- • **Antihistamine Night Defense:** Night caplets include chlorpheniramine maleate to combat runny nose and ensure restful sleep.
- • **Trusted Doctor-Recommended Brand:** Tylenol, #1 pain relief brand, trusted by millions for safe, reliable cold & flu symptom control.
- • **Maximum Strength Pain & Cough Control:** 500mg acetaminophen plus 15mg dextromethorphan HBr delivers fast, effective relief from aches, fever, and severe cough.

## Overview

Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets offer a 24-count combo pack with 16 daytime and 8 nighttime caplets. Formulated with 500mg acetaminophen for pain and fever relief, 15mg dextromethorphan HBr to suppress severe cough, and chlorpheniramine maleate in night caplets to relieve runny nose, this trusted, doctor-recommended medicine provides powerful multi-symptom cold and flu relief for adults and children 12+. Convenient and effective, it’s your go-to solution for managing sore throat, cough, aches, and congestion all day and night.

## Description

Stop your cough and sore throat before they stop you with Extra Strength Tylenol Severe Cough + Sore Throat Day/Night tablets. These extra-strength pain relief tablets provide powerful multi-symptom cold and flu relief all day. These symptoms include headaches, body aches, fever, painful sore throat, and coughs. This combo pack includes 16 day caplets formulated with 500 mg of extra strength acetaminophen for effective pain relief and 15 mg of dextromethorphan HBr cough suppressant to help calm your severe cough and 8 night caplets with chlorpheniramine maleate, a powerful antihistamine to help relieve your runny nose. This extra-strength cold relief medicine is available over the counter and can be used by adults as well as children 12 and older. Take two caplets every six hours while symptoms last and do not exceed six caplets in 24 hours. Help combat cold and flu symptoms with the power of extra strength acetaminophen from Tylenol, the #1 doctor recommended pain relief brand.

Review: Medicine sore throat - Works great. Does help with sore throat pain and doesn’t have a taste. Great value for your money. Felt better after two days of taking it.
Review: Medicine Cabinet Stable - This works when my sinus allergies act up or when I have a cold. I keep this in my medicine cabinet as a stable because this does actually work!

## Features

- 24-count combo pack, 16 day & 8 night caplets, of Extra Strength Tylenol Severe Cough + Sore Throat Day & Night caplets with acetaminophen & dextromethorphan HBr for powerful, multi-symptom relief for your painful sore throat & cough all day & night
- Extra strength pain reliever & fever reducer + cough suppressant caplets help temporarily relieve your daytime or nighttime cold symptoms like head & body aches, fever & sore throat, & painful coughs, plus, relief from your runny nose at night
- The maximum-strength, multi-symptom cold & flu medicine is formulated with 500 mg of extra strength acetaminophen to help relieve aches & pains & reduce fever, plus, 15 mg of dextromethorphan HBr cough suppressant to help calm your severe cough
- Say goodnight to your cough & sore throat. The nighttime cold medicine also contains chlorpheniramine maleate, a powerful antihistamine to help relieve your runny nose. Available over the counter, keep this combo pack with your sick care supplies
- Get fast, multi-symptom cold and flu relief with the power of extra strength acetaminophen from Tylenol, the #1 doctor recommended pain relief brand. For adults & children 12 years and older, take two caplets every six hours while symptoms last

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0DG9BW8WP |
| ASIN  | B0DG9BW8WP |
| Active Ingredients | Acetaminophen, Dextromethorphan |
| Additional Features | Unscented |
| Age Range Description | Adult |
| Best Sellers Rank | #14,088 in Health & Household ( See Top 100 in Health & Household ) #128 in Cold & Flu Medicine |
| Brand Name | Tylenol |
| Customer Reviews | 4.8 4.8 out of 5 stars (575) |
| Date First Available  | September 6, 2024 |
| Global Trade Identification Number | 00300450159342 |
| Item Dimensions | 0.75 x 2.88 x 4.47 inches |
| Item Form | Caplet |
| Manufacturer | Johnson & Johnson |
| Manufacturer  | Johnson & Johnson |
| Net Content Count | 24 Count |
| Number of Items | 1 |
| Product Benefits | Cough Relief |
| Product Dimensions  | 0.75 x 2.88 x 4.47 inches; 1.13 ounces |
| Specific Uses For Product | Cough, Sore Throat |
| Target Audience | Unisex-Adults |
| UPC | 300450159342 |
| Unit Count | 24.0 Count |

## Product Details

- **Active Ingredients:** Acetaminophen, Dextromethorphan
- **Brand:** Tylenol
- **Item dimensions L x W x H:** 0.75 x 2.88 x 4.47 inches
- **Product Benefits:** Cough Relief
- **Specific Uses For Product:** Cough, Sore Throat

## Images

![Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct - Image 1](https://m.media-amazon.com/images/I/81xwnQcJr1L.jpg)

## Available Options

This product comes in different **Style** options.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Medicine sore throat
*by S***R on January 28, 2026*

Works great. Does help with sore throat pain and doesn’t have a taste. Great value for your money. Felt better after two days of taking it.

### ⭐⭐⭐⭐⭐ Medicine Cabinet Stable
*by P***S on February 24, 2026*

This works when my sinus allergies act up or when I have a cold. I keep this in my medicine cabinet as a stable because this does actually work!

### ⭐⭐⭐⭐⭐ Best cold medicine
*by J***Z on January 6, 2026*

Helped my son heal from his cold so fast.

## Frequently Bought Together

- Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct
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**Shop now:** [https://www.desertcart.vu/products/661970350-extra-strength-severe-cough-sore-throat-day-and-night-caplets](https://www.desertcart.vu/products/661970350-extra-strength-severe-cough-sore-throat-day-and-night-caplets)

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*Product available on Desertcart Vanuatu*
*Store origin: VU*
*Last updated: 2026-03-10*