---
product_id: 678994936
title: "Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments"
brand: "frontline"
price: "VT28558"
currency: VUV
in_stock: true
reviews_count: 5
category: "Frontline"
url: https://www.desertcart.vu/products/678994936-plus-flea-and-tick-treatment-for-x-large-dogs-up
store_origin: VU
region: Vanuatu
---

# 30-day continuous protection Waterproof formula Kills fleas, eggs, larvae & ticks Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments

**Brand:** frontline
**Price:** VT28558
**Availability:** ✅ In Stock

## Summary

> 🛡️ Stay ahead of pests with Frontline Plus — because your dog deserves the best defense!

## Quick Answers

- **What is this?** Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments by frontline
- **How much does it cost?** VT28558 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.vu](https://www.desertcart.vu/products/678994936-plus-flea-and-tick-treatment-for-x-large-dogs-up)

## Best For

- frontline enthusiasts

## Why This Product

- Trusted frontline brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Month-Long Defense:** One monthly dose shields your dog for a full 30 days—never miss a beat in flea & tick protection.
- • **Waterproof & Active:** Rain or swim, the waterproof formula stays effective, continuously releasing treatment from sebaceous glands.
- • **Trusted for 20+ Years:** Join millions of pet owners who rely on Frontline’s proven, vet-recommended formula since day one.
- • **Complete Life Cycle Kill:** Targets adult fleas, eggs, larvae, and ticks—including those carrying Lyme disease—for total pest elimination.
- • **Easy Application, Big Impact:** Single-point topical treatment is quick, mess-free, and perfect for dogs up to 132 lbs.

## Overview

Frontline Plus Flea and Tick Treatment offers fast-acting, waterproof protection for extra-large dogs (89-132 lbs) with a single monthly topical dose. Formulated with fipronil and (S)-methoprene, it kills fleas, flea eggs, larvae, chewing lice, and ticks that transmit Lyme disease. Trusted by pet owners for over 20 years, it continuously replenishes through sebaceous glands, ensuring 30 days of reliable defense even if your dog gets wet. The package includes 3 easy-to-apply treatments designed for all life stages, making it the go-to solution for comprehensive flea and tick control.

## Description

Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.

Review: I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven't seen any in years! I'm glad I found it on desertcart! Because I can't afford the other stuff & too! The other stuff I don't really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she's not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder's! So thankful they still make Frontline & it works! Am definitely going to be buying more!
Review: Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away...

## Features

- Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
- Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
- Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
- FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
- Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
- Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0002J1FP8 |
| Active Ingredients | fipronil and (S)-methoprene |
| Age Range Description | All Life Stages |
| Allergen Information | Abalone Free |
| Brand Name | Frontline |
| Customer Reviews | 4.4 4.4 out of 5 stars (11,141) |
| Global Trade Identification Number | 00350604287308 |
| Included Components | Package includes 3 applicators |
| Item Form | Stick |
| Item Type Name | Topical Red box |
| Item Weight | 1.6 Ounces |
| Manufacturer | Frontline |
| Manufacturer Part Number | 72220 |
| Model Number | 72220 |
| Scent Name | Unscented |
| Target Species | Dog |
| Unit Count | 1 Count |
| Volume | 302.4 Milliliters |

## Product Details

- **Active Ingredients:** fipronil and (S)-methoprene
- **Brand:** Frontline
- **Item form:** Stick
- **Item weight:** 1.6 Ounces
- **Scent:** Unscented

## Images

![Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments - Image 1](https://m.media-amazon.com/images/I/71FiB6zP-3L.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: Does this product have an EPA number on the box?**
A: Yes it does. It's 100% USA EPA Registered and legal for sale in the USA.

**Q: What are the active ingredients?**
A: Zoom in on box, switched from advantage appears to work well.

**Q: Does the product kill ticks throughout the dogs body and not just near the application site?**
A: Throughout the body.  Our dogs have not had ticks for years, although you do need to continue to check them.

**Q: Will this work for a dog that is 210 lbs**
A: I have a 200 lb Great Dane and works for him…the best is the chew that lasts 3 months…have to get from vet and very expensive

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by T***E on 29 December 2025*

I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven't seen any in years! I'm glad I found it on Amazon! Because I can't afford the other stuff & too! The other stuff I don't really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she's not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder's! So thankful they still make Frontline & it works! Am definitely going to be buying more!

### ⭐⭐⭐⭐⭐ Review
*by S***H on 23 September 2024*

Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away...

### ⭐⭐⭐⭐⭐ Review
*by L***L on 10 March 2026*

Great product, works well.

## Frequently Bought Together

- Frontline Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments
- Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
- Frontline Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

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*Product available on Desertcart Vanuatu*
*Store origin: VU*
*Last updated: 2026-05-03*