maxxipaws maxxiSAMe Advanced SAM-e Powder Supplement - Liver, Cognitive & Joint Support for Dogs, 5.3oz

Update 10/15/2025: Hi there, me again. Now that it is 8 years later, Barney's adopted little brother Maximus is well into his senior years. He's in great shape for his age, which we estimate to be around 13 years (he's a rescue pittie), but he's started showing some signs of cognitive decline - restlessness, pacing, and panting, especially at night. We are managing his relatively mild arthritis stiffness with meds from our vet, thinking that's why he was so agitated, but the cognitive symptoms persisted. That's when I remembered how much this supplement helped our Barney all those years ago. We've been loyal to the Maxxi brand this whole time - Max gets the Omega oil and MaxxiDigest on his food daily to help with his coat and tummy (ya boy gets some serious diarrhea and gas that'll knock you out without it) - so I can't believe it took me this long to remember that MaxxiSAMe exists. Unlike Barney, Max gobbles this stuff right up with his food, no weird cheese sushi roll required. Thank you, MaxxiPaws, for continuing to put out a quality product. ---- Final Barney update 5/24/2017: This will be my final update to this review, as we unfortunately had to say goodbye to our wonderful dog Barney last week after his slow onset of degenerative myleopathy had progressed too far. I cannot say enough good things about the MaxxiDog company as they helped us find solutions to make Barney's last year+ as comfortable and happy as it could be. I truly believe that the MaxxiSAMe product had a positive effect for Barney and was key in making his last time with us a happy one, as it really seemed to help mitigate his symptoms of Canine Cognitive Dysfunction (CCD). I have changed my review to five stars to reflect this. Please continue reading below for the original review, and the other updates on how we ended up using the product. (Spoiler: The most effective way to get Barney to eat it was to do two small pumps of MaxxiOmega oil with it to make a paste, and then put the paste in American cheese like a weird little sushi roll! He never turned his nose up at this option.) Thank you again to the MaxxiDog company for your excellent product and wonderful customer service. ---- (Original review:) My dog Barney is well into his golden years and has is showing some pretty strong signs of canine cognitive dysfunction (CCD; basically, doggie dementia) such as night waking/panting, getting lost or stuck in corners, licking, digging at the floor, and fecal incontinence. So, I powered up the ol' computer and did some research. It turns out there isn't a ton you can do for it once they've got it, but there are supplements that can help manage some of the symptoms and keep it from progressing as quickly. Enter: SAMe and choline. These two seemed to pop up the most in my searches but my head was spinning about what product to buy. Well, this MaxxiSAMe stuff handily has both! Awesome! Now, a little bit about Barney - Barney has been anywhere from 77 to 90 pounds since I've known him. This dog LOVES to eat. He's not picky, either - he eats 'yard treats' (if you catch my drift) regularly, for goodness sake. He once ate a raw zucchini off the floor (and immediately threw it up, but that's beside the point). Now that we've been more careful about his portion sizes he acts like we're starving him to death (I assure you, we are not) and scavenges even more. But as soon as I put this stuff on his food, Barney went on a hunger strike. He will NOT touch the stuff. It's crazy. I even tried burying cheese in his bowl thinking he'd at least eat his way down to the cheese - NOPE. Not interested. I really wish this came in pill form. I've resorted to trying to squish the dosage up in cheese and give it to him that way, which is pretty difficult since he is on the highest dosage (1 tsp per dosage, twice a day), and the supplement needs to be inside the cheese for him to eat it. I have made some messes. I think my next attempt may involve deli meat since that won't fall apart like cheese slices... though now I have visions of Barney biting into the powder ball in the meat and causing an explosion. He's only had his full dosage(ish... the part that hasn't scattered out of the cheese all over the floor anyway) for a day or two. If I notice some improvement or come up with a better method of administration, I'll absolutely come back and edit my review. I really, really want to love this product. But for now, I give it 5 stars in theory and Barney gives it a 1 star in taste so we'll compromise and call it a 3. ---- UPDATE 4/28/2016: We went through two jars of this stuff, and multiple administration methods (since adding it straight to dry food was NOT an option). First I'll talk about the effects it has had on him, and then I will talk about how we've been giving it to him. EFFECTS: After giving him two jars of this, I didn't buy a third. After a few days of not being on it, his CCD symptoms increased fairly dramatically - walking around panting/whining at night, getting lost in corners, pooing inside, etc. He was still doing some of those things SOMETIMES, so it's possible that the timing of his symptoms was coincidental with stopping the MaxxiSAMe. However, I had forgotten just how bad his symptoms used to be, especially the night symptoms - we were all sleeping very terribly for a few days there. So I bought another jar hoping it would help him, and I think it has. We all slept through the night better the last couple of nights, anyway! This is why I've upped my rating to 4 stars (was previously 3). ADMINISTRATION: Oh boy. Well, the folks at MaxxiSAMe were kind enough to respond to my review in both email form and comment form (below) and include some ideas for getting him to take it, which is super awesome of them. Here is what we've tried, and what has and hasn't worked - 1. Paste method: Add a small amount of water to make a thick paste. Give to dog like treat. This worked for maybe a couple of weeks, and now he just turns his nose away from it when I try to give it to him this way. The MaxxiSAMe folks also suggested mixing it with something he likes, but I don't think this would work, for reasons I'll get to in a moment. 2. Soft food method: Barney was on meds that made his stomach upset for a while, so to get him to eat, I would add warm water to his dry kibble food to make it soft and appealing. I could add the MaxxiSAMe directly to the soft food and he'd eat it right up. *shrug* 3. Paste + cheese method: This is what we're doing now. I add a VERY small amount of water to make a thick paste, which I form into a ball with my fingers. Then I smash cheese around it so that none (or at least very little) of the MaxxiSAMe ball is showing. If it is showing, he will not touch the stuff - or sometimes will sort of "work" at it to get the cheese off and spit the MaxxiSAMe out. This is why I don't think it would work to mix the paste with something he enjoys: he would still know the MaxxiSAMe is in there. I think this method would work better with lunch meat, but that's not something we normally have around the house, and it goes bad faster than cheese slices. This method would probably work okay with a PillPocket type treat that has a large enough pocket. So, in conclusion, Barney still thinks the stuff is super gross which makes administration a bit of an ordeal, but I have reason to believe it might be helping his CCD so that outweighs any difficulties in giving it to him. I do still wish it came in tablet form; I picture it being like Cosequin, where it's not a coated tablet but more of a compressed powder type tablet that can be broken if needed. Thanks again to the makers of this product for supplying such a high quality product, and for responding to reviews in such a thoughtful, detailed way! ---- UPDATE 6/17/2016: After my last update, the owners of MaxxiSAMe were not content that Barney still wasn't super into the stuff. They actually sent me a free bottle of their MaxxiOmega oil to try mixing that with the MaxxiSAMe, which is super awesome of them. Turns out, it totally worked. I mix his SAMe dosage with about a pump and a half of the oil, smear it on a piece of cheese and wrap the cheese sushi-style, and he gobbles it right up. He still won't QUITE eat it without cheese (though he acts like he MIGHT when I've offered it to him), but I at least don't have to try to smash the cheese all around it to hide every speck of the MaxxiSAMe. Thank you!!

I have a 15 year old Chihuahua diagnosed with liver issues when I took him in to be neutered 14 years ago (still almost a puppy). So, he has lived with very high liver enzymes most of his life....and when I say high, extremely high to the point that most vets question if the blood panel came back correctly. Long story short, he's lived a long and good life with no symptoms up until 2 to 3 years ago. That's when I started him on this product, maxxiSAMe. I sprinkled a little on his food in the morning and at night. I never really knew what it was doing except that symptoms were NOT worsening. Well, that jar lasted over a year, but when I ran out and he was off of this for a few weeks, the strange behavior returned and became more noticeable. He was circling, disoriented, lethargic and more aggressive. I got him right back on the maxxiSAMe again when the new jar arrived. Without a doubt, the symptoms of the liver issues eased up. Now, I don't want to give false hope. I have NOT found this to be a miracle drug, and it will not cure liver damage from all I've read and researched, but I strongly believe IT HELPS PREVENT more damage to the liver and keeps dogs with liver issues stabilized to some extent. I know this to be true on my dog anyway. To end, even in the past 3 months I started switching the maxxiSAMe at nights for some hemp oil to help with my dog's arthritis, and although the hemp oil helped, the lack of the maxxiSAMe at nights was noticeable. My dog started head pressing worse than I ever saw him at nights. He got very disoriented until I got him back on this product again TWICE a day rather than just one dose in the mornings. The trick for me has been to give a little on his food in the morning and a little in the evening. My baby is old and in the very late or end stages of the liver disease, no doubt, but as long as he's eating well, comfortable and not in extreme pain, I can't and I won't put him down. He's not ready to leave this world yet, but I can strongly verify that this product has made a difference and has given him more time on earth and more quality of life than if he was not on it.

I first purchased this almost a year ago. My dog was 14 at the time, and realizing that she is getting up there in age, I wanted to provide a good supplement for her. Last year, her liver enzyme was elevated, she just looked "off", possibly deteriorating due to her age. I researched Sam- e for dogs because it's supposed to help with overall health and support her liver. Well one year later at age 15, she is still going strong! She is still very alert and energetic, even the vet guessed her age to only 10-12 years old! Her blood work came out with the liver enzyme still elevated but much better compared to last year. Everything else looks good! This supplement might just contribute to her overall health. It's not medicinal so you won't see an instant result, however with constant and long term use it will provide benefits to your dogs. The product is very easy to use, I just sprinkle a little on top of her food everyday. Because my dog is small (a 9 pound miniature poodle), the entire container lasts almost one whole year. So the product is definitely worth the price. Will recommend this especially for aging pets!

Our eldest dachshund had a very high liver enzyme count when bloods were taken, following major gastric surgery. Our vet recommended a tablet that contained various ingredients to support the liver. The tablet brought his enzymes down, but, it is very expensive for a months supply, and on some days I would find the soggy tablet later in the day hidden near the fridge freezer. Reading reviews online, I became aware of several customers who had similar issues , and had tried the Maxxi SAMe instead with great results. Had a good read up, the SAMe quantity was identical, with silybjn too, from a different source, but also several other excellent ingredients , such as vitamin B12, B6, B1, B2 inositol, and choline. These are very important for nervous system and brain function. Plus the fact , that the tub is very generous for the money. So you get more benefit for a far more resonable cost . My dog has 1/4 scoop twice a day ,which is 1.25 gms for his weight of 6.6 kg. I purchased this tub in March and will need my next tub in July . The final clincher for this product, is the advice and customer service from the manufacturer. They have a great website with a dedicated phone line. When I phoned to discuss withholding Maxxi Cardio for a few days before his dental surgery, they were extremely knowledgeable and helpful. It's unusual, in my experience, to find people so invested in getting products that benefit pets. This is possibly because they all are pet owners and use these products themselves. I also had a very nice follow up email regarding dosage of Maxxi Joint for my younger dachshund. Milo had routine bloods taken before his dental in May, since he is almost 15 and surgery not without risk . Our vet stated that for his age, the bloods were good, and liver enzymes are now only mildly elevated, which is as expected for his age and pancreatic issues. Our vet was even more impressed with his recovery at his 10 day post op check , as were we. He is a different dog and I am convinced that introducing Maxxi Cardio (which I have also reviewed) was crucial to his well being as he had become quite weak with a heart murmur. If you are tempted to try the Maxxi Paws products, then contact with the customer service will no doubt help your decision, and give you good guidance. For us , Maxxi Same and Maxxi Cardio play a big part in our dachshund's fantastic health, and have hugely improve his quality of life .

A mi perro le vá fantástico. Tiene problemas con el higado y lo necessita para vivir bien.

Buon prodotto. Difficile da reperire altrove.

Kann auch von Menschen konsumiert werden... Muss nur entsprechend dosiert werden!!!

Acheter pour aider mon Bouledogue Français qui a fait un avc. On verra avec le temps, l’efficacité du produit…