NATURDAO® DAO enzyme 1,000,000 HDU per tablet - DAO Enzyme Supplement - Histamine Block - Diamine Oxidase - Food Intolerance - 60 Extended Release Tablets

These work but they are stronger than I need. I take them 5 to 10 minutes before I eat. If I take them earlier than that, they make me feel icky. I cut them in 3's and only take before meals that have known histamine reactions. They work wonders for HI reactions. I recommend them to others.

Well it took me more time than ever to find a "non-porcine" DAO enzyme that actually works and these are a must for anyone with autoimmune issues like; MCAS, histamine intolerance, SIBO... Lyme, etc. They are not cheap, but they do help me out considerably when I am in reactive mode. I am NOT a doctor, but a overcomer of all of the above.

I don’t normally leave reviews but I feel the need to share my experience. For many years I have suffered from strange symptoms like brain fog, joint pain, low energy, and in the last 7 years, rosacea. I have had many tests run and tried everything you can imagine to try and get rid of the rosacea. Recently, I came across some information on a link between rosacea and high histamine levels/low DAO in the body. All I could think was this is me! I started researching and decided to give a DAO supplement a shot along with a low histamine diet. From the very first pill, I noticed an immediate difference after I ate. Used to, I hated eating breakfast because I always felt bad. But with the DAO my head felt clear and I did not have the normal slump period. At first I thought maybe it was a placebo effect because I desperately wanted this to be the answer for me but then my rosacea almost completely cleared up within a week of taking this supplement and I felt like I could actually think again. I highly recommend this supplement! I am going to have my DAO levels tested soon but am fairly certain what they are going to say. Hopefully, the testing will direct me to how much I need to be taking. This supplement works so good for me!! I do want to add that this pill is not a free ticket to eat whatever you want. I cannot have most chocolate (cake, candy, etc) or any type of tomato sauce/soup. I’ll still break out in a rash. That being said, my rosacea and brain fog has improved significantly with this supplement and I’m so thankful!

I've had rosacea for about six years. I've tried all kinds of creams, supplements, laser treatments, diet changes; nothing stopped the hot, painful facial flushing. After doing a ton more research and tracking my symptoms, I came to the conclusion that my rosacea is either caused or heavily influenced by a histamine intolerance or possible MCAS (which I suspect is caused by SIBO, but that's a whole nother beast). I was starting to flush after nearly every single meal, it was getting unbearable. I started experimenting, adding in several antihistamines a day along with this supplement. I slowly worked my way up to 1 entire pill since I was a bit scared of a bad reaction after reading some of the negative reviews. Luckily my body adapted fine. The first few times I took it, my chronically stuffy sinuses unclogged within literal minutes, it was weird but awesome (sadly didn't last!). More importantly, this supplement has made a HUGE decrease in my food-induced flare ups. Along with my regimen of antihistamines (h1 and h2 blockers) my after-meal flushing has become basically nonexistent, the change is almost unbelievable. Because I'm flushing less from meals, it means I'm flushing less all day long since my skin is staying calmer overall. Unfortunately it doesn't work on alcohol, I definitely still flush from that, but I had to test it lol. That leads me to the only drawback: the price. I've already gone through several boxes of these and it's only been a few months. I'm fortunate that I only need one pill for each meal and that I only eat twice a day, but man, I can't imagine if you needed several pills per meal and ate three full meals a day. And these are one of the cheapest DAO supplements on the market! Yikes. It's not sustainable, at least not for me, especially since I have a pretty large regimen of other supplements I need to pay for. I've considered 1. switching to eating one meal a day to save on costs, 2. going a strict anti-histamine diet to see if that decreases my need for the supplement, 3. growing my own pea sprouts (apparently they're high in DAO; who knew) 4. and/or cutting the pills in half to make them stretch further (you'll most likely need a pill cutter if you do this, these are HARD to cut with a knife). I even tried skipping them and just using my antihistamines only before meals to see if I could do without them but sadly, that didn't prevent a flush. As soon as I felt the flush coming on I quickly took one and my skin calmed down within minutes, so I know these are having a big impact all on their own. For now I plan to keep taking them despite my crying wallet, but I'm hoping I can get to the root cause of my histamine intolerance so that some day I no longer need them.

I have MCAS and unfortunately this triggered me. I was more nauseous and experienced higher heart rate with it. Legumes are high histamine and this may not be suitable for those with histamine toxicity / overload.

Tengo un problema de disbiosis con histaminosis y el doctor recomendó tomar DAO. El producto llegó el mismo día que lo pedí y en perfecto estado. La caja es funcional, se abre y cierra de manera práctica. Sobre sus efectos, no puedo asegurar nada porque tengo múltiples síntomas; sin embargo, últimamente me he sentido mejor, sin dermatitis ni picazón.

Muy bueno. Lo único que me ha quitado la alergia a la cerveza y a otras cosas.

Muy buen producto, me ayuda mucho con mi intolerancia a alimentos altos en histamina. Se los recomiendo ampliamente, vale la pena lo que cuesta. Tomo 5 min antes de cada alimento. Y mi *alergia* desaparece.