HPN NAD3 Clinical NAD+ Booster, Cellular Health & Natural Energy - NAD Supplement for Healthy Aging, Metabolic Support, NRF2 & Longevity, Nicotinamide Riboside & NMN Alternative, 60ct, 30-Day Supply

I am a 65 year old female who has had cancer twice, and have been in remission from stage 4 metastatic cancer for 11 years, due in part I believe to a regimen of supplements including resveratrol, quercetin, Vitamin C, Vitamin D3, and many others. I also walk 3 miles per day, and have tried to avoid sugar and refined carbs for much of that time. Throughout the years I have been following anti-aging and anti-cancer research, as a curious layperson. I have explored writings and videos by David Sinclair of Harvard, Leonard Guarente of MIT, and others, leading me to the recent reports on the postulated benefits to humans of NAD precursor, Nicotinimide Riboside. Leonard Guarente himself takes it, according to his Elyseum website. I started taking the recommended dose in early February, 2015, and can report some positive results, although I believe the dosage level is critical and probably varies widely, depending on one’s age and health status. My experience has been that the prescribed dose of 250 mg. is simply too much. It revved me up, but the rebound effect was very noticeable--exhaustion. A suitable analogy might be constantly gunning and red-lining one’s old, inefficient engine. So I cut back to a half dose every other day. Much better. I still feel energetic--and optimistic--but am not completely exhausted hours later after the initial burst of energy has waned. It would certainly seem logical that younger, healthy, and/or athletic folks already have sufficient amounts of NAD, so they probably wouldn't notice much if any improvement from supplementation with NR. However, old folks have NAD deficiency as a result of aging, and probably see a much greater benefit from supplementation with NR. which increases NAD. I am guessing that most of the folks reporting little or no benefit from NR are either younger & healthy and have plenty of NAD; or, perhaps are taking far more than they need, producing some sort of negative hormesis-like response; or are not taking complementary doses of resveratrol, or other pterostilbenes, which operate in tandem with NAD as a substrate to influence anti-aging sirtuins. An update: I am now 68 and still taking NR from various makers, who add various components along with NR (all Niagen based) and at various dosages.. The 250 mg. dose is now my standard, however, and I no longer have the exhaustion effect. I don't know why, but it is gone and I am feeling great. I always take resveratrol daily, and many other supplements as noted above. I am also considering the other NAD precursor which is starting to become available, nicotinamide mononucleotide, but the price has got to come down significantly and some major advantage over NR demonstrated. Another possible effect from taking the 250 mg. NR dose is noteworthy: my fasting blood sugar is now running in the 60's and 70's regularly, but I do not feel bad. I have been doing a form of intermittent fasting for some time, but even when I have a regular meal, a few hours later my fasting glucose is back in the 60's & 70's. I test it daily. This may in fact serve as a long-term indicator of the continued efficacy of NR. I have never had fasting glucose levels this low, before taking 250 mg. of NR daily.

Its a great product! The 1st day you take it you notice you have more energy. However, the nature of our bodies is to get used to things, so after a few days you’ll not notice what you did at first. But, it is still working hard for you! And in a couple of weeks you will notice that you are thinking clearer, your thinking is more focused, and you have a better attitude towards things. A better attitude because the mind is now ‘more together’ and therefore more efficient! I like this for me. This supplement is not about feeling super energetic all the time, feeling like a superhero. Instead, its about providing you with results that when combined with a healthy lifestyle can help you get closer to reaching your highest potential. I recommend this product. Thank you HPN!

This is my main supplement for energy and mental clarity. I take this every day and I can feel a dramatic difference when I don’t take it. I have used many other NAD supplements and this is by far my favorite. Just solid energy and mental clarity. I trust this brand to other supplements as well.

I'm not sure if it was Niagen or PQQ or Astaxanthin or pterostilbene I was taking, or the combination of them, but mind you I went for a run one day. The first time in over 6 months. I literally ran and ran and ran and ran. I could not get tired. I could not. I even threw a few sprints in during my run, but I could not get tired at all. Not even close. It was the weirdest feeling in my life. Weirdest good feeling. I didn't feel edgy or over stimulated, only normal and the fact that my run of 4 plus miles didn't prove to do anything to me whereas normally 2 miles would have me huffing and puffing. I guess it was a good feeling and overall I feel pretty good on Niagen. I'm not really sure if it did much, but I think it did. I mean I couldn't get tired at all. I'm sure it was doing something. I haven't really gone for a run since nor have I been taking Niagen religiously so I can't say much more. I usually pop 250 mg when I start feeling crummy, I think it works to pick me back up. I'm scared to take more because I feel like I'm just swallowing dollar bills. I had taken it for a week straight before I went said run. Other than that run, I couldn't tell much difference...I slept just fine though during the day time I was extremely detail oriented and much more particular than normal, but I attribute that to PQQ (which is also a miracle supplement). Anyways, 4 stars because it cost a fortune. Comeon guys lower the price so the world can enjoy this supplement. I really believe David Sinclair is on to something and Niagen was one of his recent discoveries as well as pterostilbene. I'm reluctant to buy more due to the exorbitant price.

This is a dietary supplement that is called: Nicotinamide adenine dinucleotide Go to the Internet and read about what this supplement is supposed to do with regard to perhaps the beneficial effects that that you might experience as you grow older. I have taken this supplement for several months and I have not noticed any side effects that would cause me to stop taking the supplement and I have not noted any beneficial side effects. Perhaps, the only beneficial side effects would appear on a very detailed blood chemistry, which I have NOT performed yet but will be performed at a later date. I plan to continue taking the supplement and this vendor and manufacturer are excellent as far as I know.

I'm 40 and in general good health. I already get lots of vitamins and minerals in my diet. I tried this for 30 days. I know they say it can take a couple weeks before you feel anything. Honestly, I'm not sure if I did. I felt *slightly* more energy and *slightly* clearer mental focus... but so slight, I'm not sure if it's just psychosomatic/placebo effect -or- I was just getting better sleep at the time anyway. Either way, it wasn't a significant contrast for me. Maybe I'm too young to reap its main benefits, or I'm already getting enough other healthy nutrition that my body doesn't need this. I want to believe this works and delivers on all its health promises. Honestly, I just wasn't feeling enough of a difference to continue purchasing it after I finished the first bottle. Of course, your mileage may vary. :)

I am a 62 years old gal and as a result of my lifestyle, choices in food, shopping for only safe, nontoxic products and an educated use of very high quality nutritional products for decades, I take no prescription drugs and my health markers are perfect. During my early 30's I was in a head on car accident which resulting in severe Traumatic Head Injury and experienced amnesia. I healed on the outside, but the injury to my brain resulted in internal scarring and long term changes in the way I think. Now 30 some years later, despite that fact that I run 3 business, am active outdoors, own and ride horses and generally am a wild and crazy gal, I more and more suffered from brain cloud, headaches and forgetfulness. I have used herbals over the years and I am sure that helped, but I am always looking for new developments. I read about this product and what it does, made complete sense to me. Bought my first bottle here at Amazon last week, along with Pterostilbene, 50 Mg. Have been taking two capsules of Niagen and one of Pterostilbene, every morning for the last five days first thing when I wake up. Have not changed anything else. Within 24-48 hours the difference ws incredible! No foggy weirdness. Short term memory much improved. I am impressed and thrilled. Will run through this month, take the recommended couple of days off and do again. Am hoping this result lasts long term, as it really is amazing the difference.

excelente

I have only tried this and one other brand that was 333 mg. I like the one that is 300 mg. On the forums concerning niagen its really only recommended for 35 years plus and many don't notice differences until in their 50's, because their bodies are producing adquate sirts, ie sirt 1 3 6, etc. I'm 54 with arthritis, chronic fatigue and other issues and noticed immediate results in energy but also in arthritic pain and joint issues. And had moderate weight loss. Going to stick with this in the long run. Have my parents on this as well. Whether or not it induces longevity or whether it just gives quality of life, the B3's are very needed, and this is one of them. Niacin, Niacidamide and Niagen all use different pathways with the sirt activity. You can take all 3. However tend to get headaches on niacin. They all create the sirts or increase them.

I give this product 5 star

Didnt see nor feel any difference

المنتج ممتاز

I am 80+ years old, and suffer from loosing energy very easily during the day after getting up, and not getting enough sleep on daily basis. I have tried different types of supplements including NMN and other types of vitamin in nature until the time I found this NAD3 from Amazon. I felt the results after 2 weeks taking this supplements. At first My sleep gets better and better, faster and longer up to 6 - 7 hours compared to previously 2 - 3 hours. After getting up in the morning, I feel sharp in mind and get more interested in doing many things that I felt tired in doing in the previous time. Even better I feel more energetic during the whole day, doing different types of house works, like cooking, cleaning and washing. Thanks to NAD3 and I will recommend it to my friends.