








⚡ Elevate your metabolism, gut, and immunity — because thriving after 35 is non-negotiable!
Ultimate Berberine Phytosome delivers a clinically dosed, dual-action formula combining 550 mg of highly absorbable Berberine Phytosome with 450 mg of Berberine HCL per serving. Designed for adults 35+, it supports metabolic health by activating AMPK, balancing gut microbiome, and maintaining healthy cholesterol and lipid levels. Vegan, non-GMO, gluten-free, and rigorously third-party tested, this premium supplement ensures clean, effective support for appetite, immunity, and overall wellness.












| ASIN | B0CTNWBRXR |
| ASIN | B0CTNWBRXR |
| Age Range Description | Adult |
| Allergen Information | Dairy Free, Gluten Free, Non-GMO, Preservative-Free, Soy Free |
| Best Sellers Rank | #48,929 in Health & Household ( See Top 100 in Health & Household ) #1,954 in Blended Vitamin & Mineral Supplements |
| Brand Name | Ultimate |
| Container Type | Bottle |
| Customer Reviews | 4.2 4.2 out of 5 stars (286) |
| Date First Available | July 22, 2024 |
| Diet Type | Gluten Free, Keto, Paleo, Vegan, Vegetarian |
| Dosage Form | Capsule |
| Dose Release Method | Delayed Release |
| Flavor | Unflavored |
| Is Product Expirable | Yes |
| Item Form | Capsule |
| Item Weight | 2.08 ounces |
| Manufacturer | Ultimate |
| Manufacturer | Ultimate |
| Material Features | Dairy Free, Genetically Modified Organism (GMO) Free, Gluten Free, Natural, Plant Based, Soy Free, Vegan |
| Number of Items | 1 |
| Package Quantity | 1 |
| Pill Coating | Film |
| Product Dimensions | 2.36 x 2.36 x 4.41 inches; 2.08 ounces |
| Recommended Uses For Product | Health |
| Special Ingredients | Berberine |
| Supplement Formulation | Individual Supplement |
| Total Servings Per Container | 60 |
| UPC | 860010228470 |
| Unit Count | 120 Count |
K**H
Running Better with Berberine
I’ve been taking this berberine for a bit now, and I can genuinely feel a difference. Nothing dramatic or over‑the‑top — more like my whole body quietly decided to operate a little more smoothly. There’s this steady, overall “I feel better” vibe that’s hard to miss once it kicks in. It’s also incredibly normal to take. Just like any other supplement — no weird aftertaste, no complicated timing, no hoops to jump through. I appreciate that it fits right into my routine without making me rethink my entire morning. And for anyone wondering, “phytosome” just means the berberine is paired with a plant‑based carrier to help your body absorb it more easily (basically: better delivery). My wife also takes it around that time of the month and notices it helps her feel less inflamed and more balanced, which has made both of us fans of keeping this on hand. What I like most is how consistent it feels. Berberine is known for supporting general wellness and balance, and it’s nice to feel that reflected in real life, not just on the bottle. Overall, this one earns a full five stars from me. It’s simple, effective, and has become one of those quiet little habits that makes my day run better. It's a little higher on the price-point, but as a quality supplement I feel it's worth it.
S**.
Effective blood sugar and metabolism regulation
This is a great berberine formula and worth the price in my opinion. I lost several pounds with this and appreciate how it helps with blood sugar and metabolism regulation. The formula is fantastic, as GPT summarizes: "Each capsule = 275 mg berberine phytosome (a specialized form designed for higher absorption) 225 mg berberine HCl (the traditional form) Each capsule provides ~500 mg total berberine, but because the phytosome form absorbs roughly 3–4× better, each capsule behaves more like 1,200–1,500 mg of regular berberine in terms of metabolic effect. That’s a strong, therapeutic dose." I take one capsule with my first meal of the day, and another with dinner and keep it coming on a subscription. While I try to eat somewhat healthy overall, if I have a particularly sugar-rich and carb-heavy meal, I'll take two capsules before dinner, which is basically used on movie nights where all bets are off and I eat like a teenager without a care. This supplement is great for overall health as even healthy, non-diabetic people can benefit from ongoing blood sugar and metabolism control with this natural, effective, and highly-absorbable supplement.
A**G
Dosage not sufficient for me
While this may be a good product, I’m not sure 1,000 mg once a day is sufficient for me. Other brands of Berberine have been between 1500-2400 mg per day, divided per meal. That’s the only downfall I find with this product. I give it a 4 Star for this reason 09/20/24 - Update I just received my second bottle and there’s something different with it. While the product is not expired, this bottle has a rancid smell and doesn’t seem as effective.
S**N
Unhapoy
No improvement in taking supplement.
L**S
Working for me!!!
Started taking this 7/23/25 and as of 12/23/25 I have lost 30 lbs walking, taking 1 w premier protein shake for breakfast and lunch along with 1 Golo with each meal, low card high protein sensible dinner, colon cleanse night time sleep tea. I ride exercise bike, jog on treadmill, virtual walk at home videos, outdoor walks when weather permits. I still have 50 more lbs or so to lose but this helped me and works for me. Happy 2026 New Year!
N**Y
Works for me!
I have been working my buns off and this has been a huge help. The change in the posted photograph is from May of this year (2025) to today (08/26/25). Helps with my appetite. At the end of this week I will rotate off for 2 weeks and then back on. I have stage 3A CKD and had no negative impact from this supplement on my most recent labs. I have tried other berberine supplements, but this is the one where I saw change. This is not a miracle, but it can definitely help with a structured exercise routine and tight nutrition control. I'm 52 and deep in perimenopause.
R**E
Helps me sleep better!
Definitely noticed a difference right away on my ability to sleep an increased number of consecutive hours! If I take one in the morning and one shortly before bed, I can get up to 4-5 hours in a row which is unheard of for me!
P**A
Berberine
reduced my blood sugar........incredable
Trustpilot
2 weeks ago
2 weeks ago