Each enteric-coated tablet contains 400mg S-Adenosyl Methionine tosylate disulfate, yielding 200mg of "biologically active" SAM-e. Why Buy Our SAM-e? This is the original SAM-e, S-Adenosyl-Methionine tosylate disulfate, as developed in Italy and patented in the US. The manufacturing of this product is extremely difficult requiring a dry environment and cool transport. It is then stabilized and double-enteric coated. This coating ensures absorption through the small intestine, since SAM-e is destroyed in the stomach. Insist on enteric-coating! Our SAMe tablets are produced and packaged in the USA using Italian-made SAMe. What Is SAM-e / S-Adenosyl Methionine? S-Adenosyl Methionine (SAM, SAMe or SAM-e) is an amino acid discovered in Italy in 1952, where the highest quality SAM-e is currently manufactured. Until recently, SAM-e was exceedingly expensive to produce, and therefore unavailable to the public, although it is well studied. SAM-e Improves Mood: Normally, the brain manufactures all the SAM-e it needs from methionine, but SAMe production is impaired in some people. Supplementation with SAM-e increases levels of serotonin, dopamine and phosphatides, and improves serotonin and dopamine receptor site binding. Perhaps the most striking aspect of supplementation with SAM-e, is its rapid onset of action. SAM-e and Arthritis, What We Know: SAM-e plays an important role in cartilage formation and repair. In-vitro studies have shown that SAM-e increases the blood levels of proteoglycans, the starting point of cartilage formation. SAM-e has been shown in a number of studies to bring arthritis pain relief comparable to that of NSAIDs, without their side effects. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
K**R
Saving my Life!
I was diagnosed with liver disease, which is supposedly fatal. I started taking SAMe and my jaundice went away and I am feeling so much better! Anyone with liver function problems, this helps. I am taking 3-4 tablets per day as recommended by my Dr. Just remember to start out taking one, then two and then increasing so your body can get used to it.If it works for you, BUY A LOT! They run out all the time. I guess it is popular. But this is frustrating, as I have been taking this brand for years!Okay people with liver problems, I have been taking this 5 years with 1000mg milk thistle. Last year my liver tests were normal. It is a miracle! Stick with it, maybe it will work for you too!Get with the program Virilife, you need to save lives here, running out is NOT acceptable!!!!!!!!!!!!!!!!!!!!!!!!!!!!1
E**1
I was so worried....
I was so worried that these were no longer available and they had been absent from Amazon for 6 months. I have taken other brands for my depression but the other brands caused me to be more severely depressed and right away with the taking. This is the only one that worked for me and worked well. They have standardized ingredients and are very pure if you look them up on-line and maybe this is the reason I don't have severe problems. Who knows? I see they are here today on Amazon. So,” three packages, please”. Thank you for making this product.Update: As an aside, when I first took SAM-e 20 years ago and not this one, I started out cutting the pill and letting it sit in the refrigerator. They would then be like a glob of honey. I teased out ½ a “pinhead” size piece and that is what I took. It was amazing. Later on that brand was discontinued. When I tried another brand I got way worse depression fast. It was not until I found this one many years later after have given up, that I made headway. I do NOT recommend cutting them since they are enteric coated for a reason and may cause unforeseen problems if consumed cut. I use this product for depression that came about from post-encephalitis and low cholesterol both of which can cause depression from my research and personal experience.
C**N
SAMe
The research papers about this product that I have been able to find are all short time studies with small numbers. I can report it seems to me to work quickly - within two days - lifting my mood and reducing anxiety and appears to continue to work with no ill effects 18 months later. I take it with a Vit B complex supplement as recommended.In addition to mood lifting it seems to me that I have fewer aches and pains.I note that it is not recommended in conjunction with other anti-depressants or if one has manic symptoms- but it appears to be effective with few side effects.Worthy of larger RCT trial in my humble etc
B**L
Good price, not so good expiration date
Good price. I ordered three boxes, all three had expiration dates of 12/2014, so be careful on how much you order. I will use my three boxes before then.I just started taking this product so I can't comment yet on its quality and effectiveness.
I**E
Two Stars
Just didn't do it for me..not sure what I was expecting but saw no notable change in feeling
F**U
For my Dog
These are for my dog, suggested by her veterinarian. No problems.
V**S
Making a bit of a difference in bringing my mood ...
Making a bit of a difference in bringing my mood up. Will continue to use and see if the results increase over time.
K**N
Great value!
Extremely easy to swallow pill. Great price.
Trustpilot
2 months ago
4 days ago
