Can it be installed vertical instead of horizontal inside my lorex nvr?

I don't see any reason why not. Mine is installed in a Lorex NVR, but as I recall, it mounts horizontally.

Will this work in a Desktop Computer ?

I had a bunch of issues with this in my desktop... I ended up sending it back and getting two of these Seagate FireCuda HDD 8TB Internal Hard Drive HDD - 3.5 Inch CMR SATA 6Gb/s 7200RPM 256MB Cache 300TB/year with Rescue Services (ST8000DX001)

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Description

🎯 Unlock the future of surveillance storage — never miss a frame!

OPTI NAND TECHNOLOGY - Next-gen NAND integration for enhanced data integrity and AI-driven performance.
64 HD CAMERA SUPPORT - Optimized for multi-stream smart cameras, perfect for enterprise-grade surveillance setups.
ALL FRAME AI STREAMING - Minimizes frame loss for flawless, crystal-clear video playback every time.
MASSIVE 22 TB CAPACITY - Store endless hours of high-res surveillance footage without compromise.
24 7 ENTERPRISE RELIABILITY - Built to handle continuous workloads with 7200 RPM speed and robust durability.

The Western Digital 22TB WD Purple Pro is a 3.5-inch SATA 6 Gb/s internal hard drive engineered for advanced AI-enabled surveillance systems. Featuring OptiNAND technology and AllFrame AI, it supports up to 64 HD camera streams with 512 MB cache and 7200 RPM speed, delivering enterprise-class reliability and massive storage capacity for always-on video analytics and smart security applications.

Specifications

Brand	Western Digital
Manufacturer	Western Digital Technologies, Inc.
Series	WD Purple Pro
Product Dimensions	14.71 x 10.16 x 2.62 cm; 671.32 g
Batteries	1 AAAA batteries required.
Item model number	WD221PURP-SPB9SY0
Is Discontinued By Manufacturer	No
Color	purple
Form Factor	3.5-inch
Item dimensions W x H	14.7 x 10.2 x 2.6 cm
Hard Drive Size	22 TB
Hard Disk Description	Mechanical Hard Disk
Hard Drive Interface	Serial ATA-600
Hard Disk Rotational Speed	7200 RPM
Are Batteries Included	No
Lithium Battery Energy Content	2.6 Watt Hours
Lithium Battery Packaging	Batteries contained in equipment
Lithium Battery Weight	5 g
Number Of Lithium Ion Cells	4
Item Weight	671 g

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