Rapamycin: mTOR, Autophagy & Treating mTOR Syndrome

This is an exciting idea, and becoming more popular. One thing not mentioned in the book is that in animals, rapamycin seems to shrink the thymus, which would not be very good, if true in humans. I would like to understand this better. Perhaps that will be addressed eventually by adjusting dose/frequency.

One of the best explanations on rapamycin regiment to promote my best health and longevity.

Ross Pelton has written a remarkable volume about Rapamycin. ANYONE who is interested in their health and longevity should read this book. As a health care professional for over 45 years, I cannot say enough about the material he presents!Thank you, Ross Pelton !

Like most self published books, this one would substantially benefit from a good editor, shortening and focusing it. That being said, it contains a lot of useful info, as well as links to helpful sites, including ways to obtain rapamycin. A few additions, perhaps as an appendix, would have been helpful to me: protocol for sirolimus blood testing (e.g., when after dosing, and desired values), and specific mention of companies whose rapamycin product has resulted in good or subpar blood levels.

I read this book because my doctor prescribed Rapamycin. Now I am really excited and hopeful that my heart may have a chance to function better.

I am a 77 year old male, taking a once weekly dose of Rapamyacin under the guidance of a physician in Palm Springs, California. This book has allowed me to have informed in intelligent conversations with my health provider, and alert us to the small probability that there may be side effects, this is a readable primer on the Rapamyacin‘s mechanism of action and the relevant life extending studies – – by a knowledgeable author. Dosages, possible, side effects, and relevant lab tests discussed.I Purchased the prior edition, and will be buying this second edition, which has some updates that I believe are important.

I didn't read this book, but learned about it on the Ben Greenfield podcast. I have some questions about it that I can't seem to find the answers too. I began taking Rapamycin a month ago. First I took 5mg... The next day my energy was really low, and I felt like I was coming down with something for more than a week. It was very similar to how I feel when I have reactivation of Epstein Barr. I'm VERY prone to this virus in all it's forms, i.e.. herpes, shingles, etc... I take daily valacyclovir, otherwise I would be in a constant flare of cold sores, fatigue, etc... After researching it and reading that it does in fact enhances lytic replication of Epstein-Barr virus I'm quite confused. After reading the scientific research on this, there is lots of indication that it does reactivate this virus, yet this virus is the cause of so many cancers and dementia. Can one only take Rapamycin if they aren't susceptible to HSV virus? Please someone help me understand this connection and if their is something I'm missing. Or something I can take along with Rapamycin to mitigate this effect.I didn't dare take it again a week later... I waited 3 weeks and tried a lower dose of 2 mg and had the same effect. I also got mouth sores both times.